Recent advances in cancer research: mouse models of tumorigenesis (Q34646656)

3 August 2017

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title

Recent advances in cancer research: mouse models of tumorigenesis (English)

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3 August 2017

Michaela Herzig

1

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PubMed ID

12020798

3 August 2017

Gerhard Christofori

series ordinal

2

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PubMed ID

12020798

3 August 2017

language of work or name

English

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publication date

1 June 2002

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Biochimica et Biophysica Acta

3 August 2017

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3 August 2017

1602

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3 August 2017

2

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3 August 2017

97-113

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3 August 2017

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The restriction point and control of cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

1 reference

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Molecular analysis of signal transduction by growth factors

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Nf1 gene targeting: toward models and mechanisms

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mouse models of tumor development in neurofibromatosis type 1

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mouse tumor model for neurofibromatosis type 1

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Smad3 mutant mice develop metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Linking colorectal cancer to Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Suppression of intestinal neoplasia by DNA hypomethylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The GLI gene is a member of the Kruppel family of zinc finger proteins.

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Basal cell carcinomas in mice overexpressing sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Activating Smoothened mutations in sporadic basal-cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Basal cell carcinomas in mice overexpressing Gli2 in skin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Effects of an Rb mutation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Targeted disruption of p107: functional overlap between p107 and Rb

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Essential role for oncogenic Ras in tumour maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Reversible tumorigenesis by MYC in hematopoietic lineages

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Action of Myc in vivo - proliferation and apoptosis

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https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Apoptosis control by death and decoy receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Tumor spectrum analysis in p53-mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Multiple patterns of MDM-2 deregulation in human leukemias: implications in leukemogenesis and prognosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Life-or-death decisions by the Bcl-2 protein family.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

PTEN: life as a tumor suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

10q23.3 loss of heterozygosity is higher in lymph node-positive (pT2-3,N+) versus lymph node-negative (pT2-3,N0) prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Pten is essential for embryonic development and tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Biochemistry and genetics of eukaryotic mismatch repair

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

MSH2 deficient mice are viable and susceptible to lymphoid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Genetic instabilities in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mutations of mitotic checkpoint genes in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The genetic defect in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

DNA polymerase stalling, sister chromatid recombination and the BRCA genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The role of ATM in DNA damage responses and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

DNA repair: The Nijmegen breakage syndrome protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mitotic checkpoints: from yeast to cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Characterization of MAD2B and other mitotic spindle checkpoint genes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Identification of a human mitotic checkpoint gene: hsMAD2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Clinical applications of angiogenic growth factors and their inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Angiogenesis in cancer and other diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Induction of angiogenesis during the transition from hyperplasia to neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Vascular-specific growth factors and blood vessel formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

From angiogenesis to lymphangiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A causal role for E-cadherin in the transition from adenoma to carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Involvement of chemokine receptors in breast cancer metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Development of a flexible and specific gene delivery system for production of murine tumor models

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Chromosome engineering in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

From mouse to man: generating megabase chromosome rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Requirement for a functional Rb-1 gene in murine development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Malignant melanoma in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Tumors of the retinal pigment epithelium metastasize to inguinal lymph nodes and spleen in tyrosinase-related protein 1/SV40 T antigen transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

WAP-TAg transgenic mice and the study of dysregulated cell survival, proliferation, and mutation during breast carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A bcr-v-abl oncogene induces lymphomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Retinoblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Development of pulmonary bronchiolo-alveolar adenocarcinomas in transgenic mice overexpressing murine c-myc and epidermal growth factor in alveolar type II pneumocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Prostate cancer in a transgenic mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

A transgenic mouse model of metastatic prostate cancer originating from neuroendocrine cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

New murine model for hepatocellular carcinoma: transgenic mice expressing metallothionein-ovine growth hormone fusion gene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2802%2900039-2

7 January 2021

10.1016/S0304-419X(02)00039-2

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12020798