Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice. (Q34347328)

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28 October 2019

title

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice (English)

1 reference

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28 October 2019

4

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28 October 2019

author name string

Harvey M

1

1 reference

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28 October 2019

McArthur MJ

2

1 reference

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28 October 2019

Montgomery CA Jr

3

1 reference

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28 October 2019

Bradley A

5

1 reference

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28 October 2019

Donehower LA

6

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28 October 2019

publication date

1 November 1993

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28 October 2019

language of work or name

0 references

1 reference

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28 October 2019

volume

5

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28 October 2019

issue

3

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28 October 2019

page(s)

225-229

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The p53 tumour suppressor gene

28 October 2019

cites work

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Mutations in the p53 gene occur in diverse human tumour types

21 January 2018

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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

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Prevalence and Spectrum of Germline Mutations of the p53 Gene among Patients with Sarcoma

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High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

21 January 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

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Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

21 January 2018

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

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p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

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Thymocyte apoptosis induced by p53-dependent and independent pathways

21 January 2018

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Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors

21 January 2018

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Wild-type p53 activates transcription in vitro

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p53 Mutations in Human Cancers

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7 January 2021

TP53 tumor suppressor gene: a model for investigating human mutagenesis

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7 January 2021

Rearrangement of the p53 gene in human osteogenic sarcomas

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7 January 2021

Rare occurrence of P53 gene mutations in multiple myeloma

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Mutation of p53 gene does not play a critical role in myelodysplastic syndrome and its transformation to acute leukaemia

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7 January 2021

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

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7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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7 January 2021

Germline Mutations of the p53 Tumor-Suppressor Gene in Children and Young Adults with Second Malignant Neoplasms

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7 January 2021

Friend virus-induced erythroleukemia and the multistage nature of cancer

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7 January 2021

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

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7 January 2021

Oncogenic forms of p53 inhibit p53-regulated gene expression

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7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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7 January 2021

U.S. childhood cancer deaths by cell type, 1960-68.

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7 January 2021

Apoptosis--the mechanism of cell death in dimethylnitrosamine-induced hepatotoxicity

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7 January 2021