Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 (Q28594951)

1 February 2017

title

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 (English)

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1 February 2017

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GOA release 2020-03-11

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T. Jacks

1

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1 February 2017

T. S. Shih

2

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1 February 2017

E. M. Schmitt

3

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1 February 2017

R. T. Bronson

4

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1 February 2017

A. Bernards

5

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1 February 2017

R. A. Weinberg

6

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1 February 2017

publication date

1 July 1994

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1 February 2017

language of work or name

0 references

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1 February 2017

volume

7

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1 February 2017

issue

3

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1 February 2017

page(s)

353–361

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A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1 February 2017

cites work

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The neurofibromatosis type 1 gene encodes a protein related to GAP

21 April 2017

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21 April 2017

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The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

21 April 2017

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Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

21 April 2017

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Somatic mutations in the neurofibromatosis 1 gene in human tumors

21 April 2017

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HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

21 April 2017

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A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice

21 April 2017

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splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

21 April 2017

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

Effects of an Rb mutation in the mouse

21 April 2017

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https://api.crossref.org/works/10.1038%2FNG0794-353

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 April 2017

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https://api.crossref.org/works/10.1038%2FNG0794-353

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

21 April 2017

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https://api.crossref.org/works/10.1038%2FNG0794-353

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

21 April 2017

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https://api.crossref.org/works/10.1038%2FNG0794-353

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Neurofibromatosis type 1 gene mutations in neuroblastoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Von Recklinghausen neurofibromatosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Requirement for a functional Rb-1 gene in murine development

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Role of neural crest in congenital heart disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients

21 January 2018

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Identification and characterization of the neurofibromatosis type 1 protein product

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

NF1: a prevalent cause of tumorigenesis in human cancers?

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Mutation and cancer: statistical study of retinoblastoma

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Mutations in the neurofibromatosis 1 gene in sporadic malignant melanoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Mouse neurofibromatosis type 1 cDNA sequence reveals high degree of conservation of both coding and non-coding mRNA segments

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Recurrence of a nonsense mutation in the NF1 gene causing classical neurofibromatosis type 1.

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Identification and characterization of sporadic and inherited mutations in exon 31 of the neurofibromatosis (NF1) gene

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Transgenesis by means of blastocyst-derived embryonic stem cell lines

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Bilateral pheochromocytoma-ganglioneuroma of the adrenal in type 1 neurofibromatosis

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Neural crest cells contribute to normal aorticopulmonary septation

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

A transgenic mouse model for human neurofibromatosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Persistent truncus arteriosus in the Splotch mutant mouse

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https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

An alternatively-spliced mRNA in the carboxy terminus of the neurofibromatosis type 1 (NF1) gene is expressed in muscle

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Simplified mammalian DNA isolation procedure

1 reference

https://api.crossref.org/works/10.1038%2FNG0794-353

7 January 2021

Identifiers

DOI

10.1038/NG0794-353

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017