Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). (Q34381917)

1 August 2017

title

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). (English)

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1 August 2017

2

R D Kineman

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H Kiyokawa

1

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K O Manova-Todorova

3

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V C Soares

4

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E S Hoffman

5

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M Ono

6

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D Khanam

7

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A C Hayday

8

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L A Frohman

9

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A Koff

10

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publication date

1 May 1996

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1 August 2017

language of work or name

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volume

85

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issue

5

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1 August 2017

page(s)

721-732

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Thymocyte apoptosis induced by p53-dependent and independent pathways

1 August 2017

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T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice

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TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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Inhibition of cyclin-dependent kinases by p21

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Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

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Effects of an Rb mutation in the mouse

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p27KIP1, an inhibitor of cyclin-dependent kinases

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Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells

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Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

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Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

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Growth enhancement of transgenic mice expressing human insulin-like growth factor I

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p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

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Principles of CDK regulation

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Bromodeoxyuridine in tumors and chromosomes detected with a monoclonal antibody

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

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A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology

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Cyclin-dependent regulation of G1 in mammalian fibroblasts.

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Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes

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G1 events and regulation of cell proliferation

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7 January 2021

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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7 January 2021

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

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Different roles for cyclins D1 and E in regulation of the G1-to-S transition

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Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

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A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

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Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

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7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

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7 January 2021

p21-containing cyclin kinases exist in both active and inactive states

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7 January 2021

10.1016/S0092-8674(00)81238-6

Identifiers

DOI

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1 August 2017

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