The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development (Q42492007)

1 November 2017

title

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development (English)

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Fleischmann A

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Behrens A

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Stingl L

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Carroll J

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Schlessinger J

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publication date

1 July 2000

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1 November 2017

language of work or name

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volume

102

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issue

2

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page(s)

211-220

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Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 November 2017

cites work

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7 January 2021

Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

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7 January 2021

ras oncogenes: their role in neoplasia

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7 January 2021

The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

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7 January 2021

v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis

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7 January 2021

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

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7 January 2021

Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

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7 January 2021

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

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7 January 2021

The physiology of transforming growth factor-alpha

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7 January 2021

Ras signalling and apoptosis

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7 January 2021

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

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7 January 2021

A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation

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7 January 2021

Epidermal differentiation: the bare essentials

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7 January 2021

Genetic Skin Disorders of Keratin

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7 January 2021

Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes

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7 January 2021

A Raf-independent Epidermal Growth Factor Receptor Autocrine Loop Is Necessary for Ras Transformation of Rat Intestinal Epithelial Cells

1 reference

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7 January 2021

Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

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7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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7 January 2021

The EGF/TGF alpha receptor in skin

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7 January 2021

Ras promotes cell survival in Drosophila by downregulating hid expression

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7 January 2021

Regulation of signal transduction and signal diversity by receptor oligomerization

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7 January 2021

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

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7 January 2021

The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase

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7 January 2021

TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

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7 January 2021

Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation.

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7 January 2021

Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes.

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7 January 2021

Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

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7 January 2021

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-X L and caspase-3-like proteases

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7 January 2021

The type 1 (EGFR-related) family of growth factor receptors and their ligands

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7 January 2021

Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants

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7 January 2021

Regulation of Bcl-xL expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor

1 reference

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7 January 2021

An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

1 reference

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7 January 2021

Strain-dependent epithelial defects in mice lacking the EGF receptor

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7 January 2021

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor

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7 January 2021

SH2/SH3 signaling proteins

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7 January 2021

EGF receptor signaling inhibits keratinocyte apoptosis: evidence for mediation by Bcl-XL

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7 January 2021

Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

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7 January 2021

The initiation of cell division in a contact-inhibited mammalian cell line

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7 January 2021

Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/insulin-like growth factor-1

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900026-X

7 January 2021

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900026-X

7 January 2021

The Grb2 binding domain of mSos1 is not required for downstream signal transduction

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900026-X

7 January 2021

Novel mechanisms of RTK signal generation

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7 January 2021

10.1016/S0092-8674(00)00026-X

Identifiers

DOI

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1 November 2017

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