The Hallmarks of Cancer (Q221226)

PubMed

PubMed publication ID

27 July 2022

2

R A Weinberg

R A

Weinberg

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http://interestingmedical.com/wp-content/uploads/2015/10/h979.jpg

PubMed

PubMed publication ID

27 July 2022

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January 2000

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language of work or name

English

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described at URL

language of work or name

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100

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issue

1

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page(s)

57–70

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publication type of scholarly work

review article

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Apoptosis control by death and decoy receptors

Europe PubMed Central

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How tumors become angiogenic

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Telomerase and the maintenance of chromosome ends

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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Changing views of the role of matrix metalloproteinases in metastasis

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The INK4a/ARF tumor suppressor: one gene—two products—two pathways

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The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene

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A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

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At the crossroads of inflammation and tumorigenesis

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Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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Matrix metalloproteinases and the development of cancer

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Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

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erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

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Mechanisms and consequences of activation of protein kinase B/Akt

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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A Matter of Life and Cell Death

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The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin.

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Mitochondria and apoptosis

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Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse

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Creation of human tumour cells with defined genetic elements

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Telomerase activity is sufficient to allow transformed cells to escape from crisis

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

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A proinflammatory cytokine inhibits p53 tumor suppressor activity

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Requirement for the CD95 Receptor-Ligand Pathway in c-Myc-Induced Apoptosis

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Genetic manipulation of vascular adhesion molecules in mice

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Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells

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Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

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Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease

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v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation

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The neural cell adhesion molecule NCAM in multiple myeloma

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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Lessons from hereditary colorectal cancer

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ONCOGENESIS: Landscaping the Cancer Terrain

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Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes

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Genetic instabilities in human cancers

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p53, the cellular gatekeeper for growth and division

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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The clonal evolution of tumor cell populations

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Oncogenes as inducers of tumor angiogenesis

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How many mutations are required for tumorigenesis? Implications from human cancer data

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Ras - a versatile cellular switch

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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A survey of telomerase activity in human cancer

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Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas

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Tumorigenic conversion of immortal human keratinocytes through stromal cell activation

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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p53-dependent apoptosis suppresses tumor growth and progression in vivo

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Caspases: Enemies Within

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

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Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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VEGFs, receptors and angiogenesis

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Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity

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The retinoblastoma protein and cell cycle control

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ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

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The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

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Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

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Cell death: the significance of apoptosis

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Growth factor receptor tyrosine kinases

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Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

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Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

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15 December 2024

https://opencitations.net/index/api/v1/citations/10.1002/J.1460-2075.1992.TB05245.X

Identifiers

DOI

10.1016/S0092-8674(00)81683-9

1 reference

Consolidated OpenCitations Corpus – April 2017

Microsoft Academic ID (discontinued)

1 reference

28 October 2013

2776199265

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100280

1 reference

Consolidated OpenCitations Corpus – April 2017

100280

PubMed publication ID

10647931

1 reference

Consolidated OpenCitations Corpus – April 2017