Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL. (Q54147247)

25 May 2018

title

Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL. (English)

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25 May 2018

author

Fabien Guidez

2

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25 May 2018

Pier Paolo Pandolfi

7

object named as

P P Pandolfi

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25 May 2018

L Z He

1

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25 May 2018

C Tribioli

3

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25 May 2018

D Peruzzi

4

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25 May 2018

M Ruthardt

5

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A Zelent

6

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25 May 2018

language of work or name

English

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publication date

1 February 1998

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25 May 2018

published in

Nature Genetics

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25 May 2018

volume

18

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25 May 2018

page(s)

126-135

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25 May 2018

issue

2

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25 May 2018

https://scigraph.springernature.com/pub.10.1038/ng0298-126

exact match

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cites work

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

21 January 2018

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A novel zinc finger coiled-coil domain in a family of nuclear proteins

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Sequence-specific DNA binding and transcriptional regulation by the promyelocytic leukemia zinc finger protein.

21 January 2018

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Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies

21 January 2018

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Histone acetylation in chromatin structure and transcription

21 January 2018

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Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein

21 January 2018

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

21 January 2018

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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

21 January 2018

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Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

21 January 2018

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Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

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A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

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SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia

21 January 2018

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

21 January 2018

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

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Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Acute promyelocytic leukemia

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7 January 2021

Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

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Retinoids in cancer therapy

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7 January 2021

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

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7 January 2021

Multimeric complexes of the PML-retinoic acid receptor alpha fusion protein in acute promyelocytic leukemia cells and interference with retinoid and peroxisome-proliferator signaling pathways

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7 January 2021

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors

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https://api.crossref.org/works/10.1038%2FNG0298-126

7 January 2021

Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

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7 January 2021

Chronic myeloid leukemia

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7 January 2021

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

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https://api.crossref.org/works/10.1038%2FNG0298-126

7 January 2021

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia

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7 January 2021

Histone deacetylase activity is required for full transcriptional repression by mSin3A

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7 January 2021

Immunodetection of multiple species of retinoic acid receptor alpha: evidence for phosphorylation

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7 January 2021

The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML

1 reference

https://api.crossref.org/works/10.1038%2FNG0298-126

7 January 2021

Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias

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7 January 2021

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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https://api.crossref.org/works/10.1038%2FNG0298-126

7 January 2021

Identifiers

DOI

10.1038/NG0298-126

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25 May 2018

Dimensions Publication ID

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1 reference

25 May 2018