Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine adjuvants (Q37981769)

26 August 2017

Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine adjuvants (English)

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26 August 2017

1 reference

1 reference

Colleen Olive

1

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26 August 2017

1 February 2012

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Expert Review of Vaccines

26 August 2017

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26 August 2017

11

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26 August 2017

237-256

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26 August 2017

2

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Pathogen recognition in the innate immune response.

26 August 2017

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Pathogen recognition by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Pattern recognition receptors and control of adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Regulation of adaptive immunity by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor control of the adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Unraveling V(D)J recombination; insights into gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Leucine-rich repeats and pathogen recognition in Toll-like receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Pathogen recognition by innate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Inflammatory lipoproteins purified from a toxigenic and arthritogenic strain of Mycoplasma arthritidis are dependent on Toll-like receptor 2 and CD14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Discrimination of bacterial lipoproteins by Toll-like receptor 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Staphylococcus aureus peptidoglycan is a toll-like receptor 2 activator: a reevaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Interactions of Toll-like receptors with fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

CD36 is a sensor of diacylglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

21 January 2018

TLR accessory molecules

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

LPS/TLR4 signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Role of the Toll/interleukin-1 receptor signaling pathway in host resistance and pathogenesis during infection with protozoan parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 4-dependent activation of dendritic cells by a retrovirus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Of mice and man: TLR11 (finally) finds profilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

A toll-like receptor that prevents infection by uropathogenic bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Respiratory syncytial virus induces TLR3 protein and protein kinase R, leading to increased double-stranded RNA responsiveness in airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

TLR9-Dependent Recognition of MCMV by IPC and DC Generates Coordinated Cytokine Responses that Activate Antiviral NK Cell Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

TLR signalling and the function of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

How Toll-like receptors signal: what we know and what we don't know

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Current views of toll-like receptor signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptors in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Ubiquitylation in innate and adaptive immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Function of Nod-like receptors in microbial recognition and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Intracellular NOD-like receptors in host defense and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod1-mediated endothelial cell activation by Chlamydophila pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Regulation of Nod1-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Activation of innate immune antiviral responses by Nod2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Inflammasomes: guardians of cytosolic sanctity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The inflammasomes: guardians of the body

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Adenovirus membrane penetration activates the NLRP3 inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Inflammasomes as mediators of immunity against influenza virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The NLRP3 inflammasome detects encephalomyocarditis virus and vesicular stomatitis virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Measles virus V protein inhibits NLRP3 inflammasome-mediated interleukin-1β secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Influenza virus activates inflammasomes via its intracellular M2 ion channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The Nalp3 inflammasome is essential for the development of silicosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Signaling by ROS drives inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Critical functions of priming and lysosomal damage for NLRP3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal -Glucan

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Fungal zymosan and mannan activate the cryopyrin inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

NLRC4/IPAF: a CARD carrying member of the NLR family

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Differential requirements for NAIP5 in activation of the NLRC4 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

NALPs: a novel protein family involved in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The roles of TLRs, RLRs and NLRs in pathogen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Recognition of viruses by cytoplasmic sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T-helper cell type 1 responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Dual stimulation of MyD88-dependent Toll-like receptors induces synergistically enhanced production of inflammatory cytokines in murine bone marrow-derived dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Selective synergy in anti-inflammatory cytokine production upon cooperated signaling via TLR4 and TLR2 in murine conventional dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Applying TLR synergy in immunotherapy: implications in cutaneous leishmaniasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Enhanced antibody responses to a detoxified lipopolysaccharide-group B meningococcal outer membrane protein vaccine are due to synergistic engagement of Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Regulation of the activity of an adeno-associated virus vector cancer vaccine administered with synthetic Toll-like receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cooperation of Toll-like receptor signals in innate immune defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Negative regulation of MyD88-dependent signaling by IL-10 in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Morphine inhibits murine dendritic cell IL-23 production by modulating Toll-like receptor 2 and Nod2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cooperative stimulation of dendritic cells by Cryptococcus neoformans mannoproteins and CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Selected commensal-related bacteria and Toll-like receptor 3 agonist combinatorial codes synergistically induce interleukin-12 production by dendritic cells to trigger a T helper type 1 polarizing programme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Current adjuvants and new perspectives in vaccine formulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

DNA released from dying host cells mediates aluminum adjuvant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

MF59 adjuvant: the best insurance against influenza strain diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Antibody persistence and response to 2010-2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Eleven years of Inflexal V-a virosomal adjuvanted influenza vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Recent clinical experience with vaccines using MPL- and QS-21-containing adjuvant systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

(How) do aluminium adjuvants work?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Selective activation of the p38 MAPK pathway by synthetic monophosphoryl lipid A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Mechanism of impaired NLRP3 inflammasome priming by monophosphoryl lipid A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Use of defined TLR ligands as adjuvants within human vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Phase 1 trial of the Plasmodium falciparum blood stage vaccine MSP1(42)-C1/Alhydrogel with and without CPG 7909 in malaria naïve adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

PolyI:polyC12U adjuvant-combined intranasal vaccine protects mice against highly pathogenic H5N1 influenza virus variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Flagellin as an adjuvant: cellular mechanisms and potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Novel protein-based pneumococcal vaccines administered with the Th1-promoting adjuvant IC31 induce protective immunity against pneumococcal disease in neonatal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The two component adjuvant IC31® potentiates the protective immunity induced by a dengue 2 recombinant fusion protein in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Ag85B-ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

The vesicle size of DDA:TDB liposomal adjuvants plays a role in the cell-mediated immune response but has no significant effect on antibody production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Development and preclinical safety evaluation of a new therapeutic HIV-1 vaccine based on 18 T-cell minimal epitope peptides applying a novel cationic adjuvant CAF01.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Enhanced IL-10 production by TLR4- and TLR2-primed dendritic cells upon TLR restimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

A comparative analysis of cytokine responses, cell surface marker expression and MAPKs in DCs matured with LPS compared with a panel of TLR ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

Nod1-Mediated Innate Immune Recognition of Peptidoglycan Contributes to the Onset of Adaptive Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.11.189

21 January 2018

Identifiers

DOI

10.1586/ERV.11.189

1 reference

26 August 2017

1 reference

PubMed ID

22309671