IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction (Q24318426)

Fas associated via death domain

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TANK binding kinase 1

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Receptor interacting serine/threonine kinase 1

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Interferon regulatory factor 7

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positive regulation of transcription by RNA polymerase II

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author

Shizuo Akira

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Ken J. Ishii

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Cevayir Çoban

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Cevayir Coban

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author name string

Taro Kawai

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Ken Takahashi

2

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Shintaro Sato

3

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Himanshu Kumar

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Hiroki Kato

6

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Osamu Takeuchi

Innate immune recognition

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publication date

October 2005

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language of work or name

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6

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issue

10

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page(s)

981-8

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cites work

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20 April 2017

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Toll-like receptor signalling

20 April 2017

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

20 April 2017

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Triggering the interferon antiviral response through an IKK-related pathway

20 April 2017

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

20 April 2017

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

20 April 2017

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

20 April 2017

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Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

20 April 2017

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

20 April 2017

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

20 April 2017

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The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

20 April 2017

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Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

20 April 2017

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NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

20 April 2017

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NF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylation

20 April 2017

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Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

20 April 2017

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Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon

20 April 2017

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CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex.

20 April 2017

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Cell type-specific involvement of RIG-I in antiviral response

20 April 2017

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

20 April 2017

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7 January 2021

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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7 January 2021

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

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7 January 2021

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

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7 January 2021

The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets

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7 January 2021

Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation

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7 January 2021

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

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7 January 2021

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

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7 January 2021

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

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7 January 2021

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

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7 January 2021

Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection

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7 January 2021

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

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7 January 2021

Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation

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7 January 2021

A FADD-dependent innate immune mechanism in mammalian cells

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7 January 2021

Identification of two additional translation products from the matrix (M) gene that contribute to vesicular stomatitis virus cytopathology

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7 January 2021

Cutting Edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation

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7 January 2021

IFN Regulatory Factor 3-Dependent Induction of Type I IFNs by Intracellular Bacteria Is Mediated by a TLR- and Nod2-Independent Mechanism

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7 January 2021

Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1

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7 January 2021

CpG RNA: identification of novel single-stranded RNA that stimulates human CD14+CD11c+ monocytes

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7 January 2021