Novel protein-based pneumococcal vaccines administered with the Th1-promoting adjuvant IC31 induce protective immunity against pneumococcal disease in neonatal mice (Q35665351)

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scientific article published on 24 October 2011

Language	Label	Description	Also known as
English	Novel protein-based pneumococcal vaccines administered with the Th1-promoting adjuvant IC31 induce protective immunity against pneumococcal disease in neonatal mice	scientific article published on 24 October 2011

Statements

scholarly article

1 reference

Europe PubMed Central

9 August 2017

Novel protein-based pneumococcal vaccines administered with the Th1-promoting adjuvant IC31 induce protective immunity against pneumococcal disease in neonatal mice (English)

1 reference

Europe PubMed Central

9 August 2017

pneumococcal vaccine

1 reference

based on heuristic

inferred from title

Ingileif Jonsdottir

4

object named as

Ingileif Jonsdottir

0 references

author name string

Thorunn Asta Olafsdottir

1

1 reference

Europe PubMed Central

9 August 2017

Karen Lingnau

2

1 reference

Europe PubMed Central

9 August 2017

Eszter Nagy

3

1 reference

Europe PubMed Central

9 August 2017

language of work or name

0 references

publication date

24 October 2011

1 reference

Europe PubMed Central

9 August 2017

Infection and Immunity

1 reference

Europe PubMed Central

9 August 2017

80

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Europe PubMed Central

9 August 2017

461-468

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Europe PubMed Central

9 August 2017

1

1 reference

Europe PubMed Central

9 August 2017

T(H)17-based vaccine design for prevention of Streptococcus pneumoniae colonization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Vaccine adjuvants: putting innate immunity to work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Live recombinant Salmonella Typhi vaccines constructed to investigate the role of rpoS in eliciting immunity to a heterologous antigen

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Global serotype distribution among Streptococcus pneumoniae isolates causing otitis media in children: potential implications for pneumococcal conjugate vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

B-cell responses to vaccination at the extremes of age.

1 reference

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12 July 2018

Pneumococcal surface adhesin A (PsaA): a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Interleukin-17A mediates acquired immunity to pneumococcal colonization

1 reference

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12 July 2018

The novel adjuvant IC31 strongly improves influenza vaccine-specific cellular and humoral immune responses in young adult and aged mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Protection against nasopharyngeal colonization by Streptococcus pneumoniae is mediated by antigen-specific CD4+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies

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12 July 2018

Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998-2004.

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12 July 2018

Antibody-independent, CD4+ T-cell-dependent protection against pneumococcal colonization elicited by intranasal immunization with purified pneumococcal proteins

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12 July 2018

Invasive pneumococcal disease caused by nonvaccine serotypes among alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage

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12 July 2018

Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Antibody-independent, interleukin-17A-mediated, cross-serotype immunity to pneumococci in mice immunized intranasally with the cell wall polysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Antibodies to conserved pneumococcal antigens correlate with, but are not required for, protection against pneumococcal colonization induced by prior exposure in a mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Protein serine/threonine kinase StkP positively controls virulence and competence in Streptococcus pneumoniae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Th1-directing adjuvants increase the immunogenicity of oligosaccharide-protein conjugate vaccines related to Streptococcus pneumoniae type 3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Reverse vaccinology

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

The contribution of specific pneumococcal serogroups to different disease manifestations: implications for conjugate vaccine formulation and use, part II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Which pneumococcal serogroups cause the most invasive disease: implications for conjugate vaccine formulation and use, part I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Comparison of the PspA sequence from Streptococcus pneumoniae EF5668 to the previously identified PspA sequence from strain Rx1 and ability of PspA from EF5668 to elicit protection against pneumococci of different capsular types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Oral immunization with PspA elicits protective humoral immunity against Streptococcus pneumoniae infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

First and second dose antibody responses to pneumococcal polysaccharide vaccine in infants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.

1 reference

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12 July 2018

Polysaccharide-protein conjugates: a new generation of vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

12 July 2018

PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type

1 reference

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12 July 2018

Infections caused by Streptococcus pneumoniae: clinical spectrum, pathogenesis, immunity, and treatment

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12 July 2018

Th17/Th1 biased immunity to the pneumococcal proteins PcsB, StkP and PsaA in adults of different age.

1 reference

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25 September 2018

Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

25 September 2018

IC31, a two-component novel adjuvant mixed with a conjugate vaccine enhances protective immunity against pneumococcal disease in neonatal mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

25 September 2018

Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

25 September 2018

Defective cell wall synthesis in Streptococcus pneumoniae R6 depleted for the essential PcsB putative murein hydrolase or the VicR (YycF) response regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

25 September 2018

Constitutive expression of PcsB suppresses the requirement for the essential VicR (YycF) response regulator in Streptococcus pneumoniae R6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255653

25 September 2018

Changing Epidemiology of Invasive Pneumococcal Disease in Canada, 1998–2007: Update from the Calgary‐Area Streptococcus pneumoniae Research (CASPER) Study

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15 November 2018

A eukaryotic-type serine/threonine protein kinase StkP of Streptococcus pneumoniae acts as a dimer in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigenome technology: a novel approach for the selection of bacterial vaccine candidate antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IC31, a novel adjuvant signaling via TLR9, induces potent cellular and humoral immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of pneumococcal disease by vaccination: does serotype replacement matter?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of pH in modified ELISA procedures used for the estimation of functional antibody affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody response to pneumococcal vaccination in children younger than five years of age

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

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Antibody response to 14-valent pneumococcal capsular polysaccharide vaccine in pre-school age children

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

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Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/22025519

12 December 2020

based on heuristic

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Identifiers

10.1128/IAI.05801-11

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

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