The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response (Q29620414)

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Tschopp J

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Muruve DA

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Pétrilli V

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Zaiss AK

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White LR

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Clark SA

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Ross PJ

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Parks RJ

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language of work or name

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publication date

6 March 2008

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volume

452

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page(s)

103-7

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issue

7183

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Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors

30 April 2017

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7 January 2021

Innate immune recognition of, and regulation by, DNA.

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

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Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis

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Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

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Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

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Nod-like proteins in immunity, inflammation and disease

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The inflammasome: a danger sensing complex triggering innate immunity

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Neutrophils interact with adenovirus vectors via Fc receptors and complement receptor 1.

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Development and characterization of novel empty adenovirus capsids and their impact on cellular gene expression

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Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA

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Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

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Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.

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Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

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7 January 2021

Type I interferon signaling is required for activation of the inflammasome during Francisella infection

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7 January 2021

Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways

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7 January 2021

Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator

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7 January 2021

Interleukin-18 protects mice against acute herpes simplex virus type 1 infection.

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7 January 2021

A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection.

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7 January 2021

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

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7 January 2021

Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis

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7 January 2021

NALP1 in vitiligo-associated multiple autoimmune disease

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7 January 2021

Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10.

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7 January 2021

Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid

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7 January 2021

Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo

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7 January 2021

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

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7 January 2021

Gout-associated uric acid crystals activate the NALP3 inflammasome

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7 January 2021

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18288107

Identifiers

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

3248591

1050441844

0 references

3248591

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18288107

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017