IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9 (Q28507728)

Inhibitor of nuclear factor kappa-B kinase subunit alpha

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

8

Shizuo Akira

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Osamu Ohara

object named as

Osamu Ohara

7

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ORCID Public Data File 2021

author name string

Katsuaki Hoshino

1

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24 January 2017

Takahiro Sugiyama

2

1 reference

24 January 2017

Mitsuru Matsumoto

3

1 reference

24 January 2017

Takashi Tanaka

4

1 reference

24 January 2017

Masuyoshi Saito

5

1 reference

24 January 2017

Hiroaki Hemmi

6

1 reference

24 January 2017

Tsuneyasu Kaisho

Toll-like receptors and innate immunity

9

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24 January 2017

language of work or name

English

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publication date

13 April 2006

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24 January 2017

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24 January 2017

440

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24 January 2017

7086

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24 January 2017

949–953

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24 January 2017

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https://api.crossref.org/works/10.1038%2FNATURE04641

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Recognition of single-stranded RNA viruses by Toll-like receptor 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

The immunobiology of the TLR9 subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Plasmacytoid dendritic cells in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

IRF-7 is the master regulator of type-I interferon-dependent immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

21 January 2018

Signaling to NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

IkappaB kinase alpha is essential for mature B cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641

Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04641