IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway (Q28190704)

5

0 references

Tom Maniatis

9

object named as

Tom Maniatis

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Douglas T Golenbock

6

object named as

Douglas T Golenbock

0 references

Anthony J Coyle

7

object named as

Anthony J Coyle

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author name string

Katherine A Fitzgerald

1

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Sarah M McWhirter

2

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Kerrie L Faia

3

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Daniel C Rowe

4

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Sha-Mei Liao

Triggering the interferon response: the role of IRF-3 transcription factor

8

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language of work or name

English

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publication date

May 2003

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published in

Nature Immunology

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volume

4

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page(s)

491-6

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issue

5

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cites work

1 reference

7 January 2021

Regulation of RANTES chemokine gene expression requires cooperativity between NF-kappa B and IFN-regulatory factor transcription factors

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On the role of IRF in host defense

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Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways

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Control of IRF-3 activation by phosphorylation

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7 January 2021

Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3

1 reference

7 January 2021

Multiple signaling pathways leading to the activation of interferon regulatory factor 3.

1 reference

7 January 2021

Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation

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7 January 2021

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

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7 January 2021

JNK2 and IKKbeta are required for activating the innate response to viral infection

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7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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7 January 2021

Activation of NF-kappaB by double-stranded RNA (dsRNA) in the absence of protein kinase R and RNase L demonstrates the existence of two separate dsRNA-triggered antiviral programs

1 reference

7 January 2021

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

1 reference

7 January 2021

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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7 January 2021

A universal role for MyD88 in TLR/IL-1R-mediated signaling

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7 January 2021

IRAK: a kinase associated with the interleukin-1 receptor

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7 January 2021

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

1 reference

7 January 2021

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

7 January 2021

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

1 reference

7 January 2021

TIRAP: an adapter molecule in the Toll signaling pathway

1 reference

7 January 2021

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

1 reference

7 January 2021

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

1 reference

7 January 2021

Toll signaling: the TIReless quest for specificity

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7 January 2021

Missing pieces in the NF-kappaB puzzle

1 reference

7 January 2021

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

1 reference

7 January 2021

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

1 reference

7 January 2021

NAK is an IkappaB kinase-activating kinase

1 reference

7 January 2021

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

1 reference

7 January 2021

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

7 January 2021

Structure and function of the interferon-beta enhanceosome

1 reference

7 January 2021

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

1 reference

7 January 2021

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

1 reference

7 January 2021

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

1 reference

7 January 2021

Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling

1 reference

7 January 2021

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

1 reference

7 January 2021

Innate immune recognition

1 reference

7 January 2021

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

1 reference

7 January 2021

Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA.

1 reference

7 January 2021

Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

1 reference

7 January 2021

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

7 January 2021

Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein-protein interactions

1 reference

7 January 2021

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

1 reference

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI921

1 reference

Consolidated OpenCitations Corpus – April 2017

320318

320318

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference