Structure, function and mechanism of the anaphase promoting complex (APC/C). (Q37811107)

23 August 2017

Structure, function and mechanism of the anaphase promoting complex (APC/C). (English)

1 reference

23 August 2017

David Barford

1

1 reference

23 August 2017

22 November 2010

1 reference

Quarterly Reviews of Biophysics

23 August 2017

1 reference

23 August 2017

44

1 reference

23 August 2017

153-190

1 reference

23 August 2017

2

1 reference

Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C

23 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The anaphase-promoting complex: it's not just for mitosis any more.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Crystal structure of the N-terminal domain of anaphase-promoting complex subunit 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mutual inhibition of separase and Cdk1 by two-step complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Degradation of the kinesin Kip1p at anaphase onset is mediated by the anaphase-promoting complex and Cdc20p

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cyclin is degraded by the ubiquitin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Proximity-induced activation of human Cdc34 through heterologous dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cut2 proteolysis required for sister-chromatid seperation in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Under arrest in mitosis: Cdc20 dies twice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Calcium elevation at fertilization coordinates phosphorylation of XErp1/Emi2 by Plx1 and CaMK II to release metaphase arrest by cytostatic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Identification of a cullin homology region in a subunit of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Multiprotein expression strategy for structural biology of eukaryotic complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

An architectural map of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Roles of the anaphase-promoting complex/cyclosome and of its activator Cdc20 in functional substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Two different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Modulation of the mitotic regulatory network by APC-dependent destruction of the Cdh1 inhibitor Acm1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Finishing mitosis, one step at a time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A novel destruction sequence targets the meiotic regulator Spo13 for anaphase-promoting complex-dependent degradation in anaphase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cell cycle control: a complex issue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The APC subunit Doc1 promotes recognition of the substrate destruction box.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase-promoting complex stabilizing the association of Cdc16 and Cdc27

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The CCT chaperonin promotes activation of the anaphase-promoting complex through the generation of functional Cdc20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Assembly of an APC-Cdh1-substrate complex is stimulated by engagement of a destruction box.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Yeast Hct1 is a regulator of Clb2 cyclin proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Independent regulation of synaptic size and activity by the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Recognition of the polyubiquitin proteolytic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Precise destruction: an emerging picture of the APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Securin and B-cyclin/CDK are the only essential targets of the APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Functionally distinct isoforms of Cik1 are differentially regulated by APC/C-mediated proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Physiological functions of the HECT family of ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Chaperone-mediated pathway of proteasome regulatory particle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Sequential E2s drive polyubiquitin chain assembly on APC targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The CRY box: a second APCcdh1-dependent degron in mammalian cdc20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The processivity of multiubiquitination by the APC determines the order of substrate degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mitosis: a matter of getting rid of the right protein at the right time

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Detection of sequential polyubiquitylation on a millisecond timescale

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mechanisms underlying ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Function and regulation of cullin-RING ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The anaphase promoting complex/cyclosome: a machine designed to destroy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mnd2, an essential antagonist of the anaphase-promoting complex during meiotic prophase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mitotic regulation of the human anaphase-promoting complex by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Apc10 and Ste9/Srw1, two regulators of the APC-cyclosome, as well as the CDK inhibitor Rum1 are required for G1 cell-cycle arrest in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Segregating sister genomes: the molecular biology of chromosome separation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The spindle-assembly checkpoint in space and time

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Molecular mechanisms of proteasome assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Calcineurin is required to release Xenopus egg extracts from meiotic M phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cohesins: chromosomal proteins that prevent premature separation of sister chromatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The E2-C vihar is required for the correct spatiotemporal proteolysis of cyclin B and itself undergoes cyclical degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A mutual inhibition between APC/C and its substrate Mes1 required for meiotic progression in fission yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Fission yeast Slp1: an effector of the Mad2-dependent spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Acm1 is a negative regulator of the CDH1-dependent anaphase-promoting complex/cyclosome in budding yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Securin regulates entry into M-phase by modulating the stability of cyclin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A repetitive sequence in subunits of the 26S proteasome and 20S cyclosome (anaphase-promoting complex).

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Protein metamorphosis: the two-state behavior of Mad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A complex degradation signal in Cyclin A required for G1 arrest, and a C-terminal region for mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The APC11 RING-H2 finger mediates E2-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Structural analysis of Bub3 interactions in the mitotic spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Identification of human APC10/Doc1 as a subunit of anaphase promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Positive feedback sharpens the anaphase switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Lingering mysteries of ubiquitin-chain assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cell cycle-dependent degradation of the Saccharomyces cerevisiae spindle motor Cin8p requires APC(Cdh1) and a bipartite destruction sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Role of Hcn1 and its phosphorylation in fission yeast anaphase-promoting complex/cyclosome function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Building ubiquitin chains: E2 enzymes at work

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The role of the destruction box and its neighbouring lysine residues in cyclin B for anaphase ubiquitin-dependent proteolysis in fission yeast: defining the D-box receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cell cycle-regulated recognition of the destruction box of cyclin B by the APC/C in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Inhibition of APCCdh1 activity by Cdh1/Acm1/Bmh1 ternary complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Dual inhibition of sister chromatid separation at metaphase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Defining the role of Emi1 in the DNA replication-segregation cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

RING domain E3 ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Different phosphorylation states of the anaphase promoting complex in response to antimitotic drugs: a quantitative proteomic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

21 January 2018

Securin' M-phase entry.

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

TPR proteins as essential components of the yeast cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Temporal and spatial control of cyclin B1 destruction in metaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

p62cdc23 of Saccharomyces cerevisiae: a nuclear tetratricopeptide repeat protein with two mutable domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cdc20: a WD40 activator for a cell cycle degradation machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Identification of a physiological E2 module for the human anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Insights into anaphase promoting complex TPR subdomain assembly from a CDC26–APC6 structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

UbcH10 has a rate-limiting role in G1 phase but might not act in the spindle checkpoint or as part of an autonomous oscillator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Unique D box and KEN box sequences limit ubiquitination of Acm1 and promote pseudosubstrate inhibition of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Coactivator functions in a stoichiometric complex with anaphase-promoting complex/cyclosome to mediate substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Getting into position: the catalytic mechanisms of protein ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Pseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The yeast APC/C subunit Mnd2 prevents premature sister chromatid separation triggered by the meiosis-specific APC/C-Ama1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Transient activation of calcineurin is essential to initiate embryonic development in Xenopus laevis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Phosphorylation of Erp1 by p90rsk is required for cytostatic factor arrest in Xenopus laevis eggs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-kappaB precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Budding yeast RSI1/APC2, a novel gene necessary for initiation of anaphase, encodes an APC subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Mitotic regulation of the APC activator proteins CDC20 and CDH1

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Budding yeast Cdc20: a target of the spindle checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Systematic analysis of human protein complexes identifies chromosome segregation proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

Identification of BIME as a subunit of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

Snap helix with knob and hole: essential repeats in S. pombe nuclear protein nuc2+

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

The KEN box regulates Clb2 proteolysis in G1 and at the metaphase-to-anaphase transition

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

What curves alpha-solenoids? Evidence for an alpha-helical toroid structure of Rpn1 and Rpn2 proteins of the 26 S proteasome

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2.

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

A Role for the Fizzy/Cdc20 Family of Proteins in Activation of the APC/C Distinct from Substrate Recruitment

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

Phosphorylation of Cdc20/fizzy negatively regulates the mammalian cyclosome/APC in the mitotic checkpoint

1 reference

https://api.crossref.org/works/10.1017%2FS0033583510000259

7 January 2021

10.1017/S0033583510000259

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

21092369