Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex (Q28199187)

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E Freed

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J Y Hsu

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E R Kramer

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J M Peters

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P K Jackson

Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage

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publication date

1 June 2001

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language of work or name

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105

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issue

5

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page(s)

645-55

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cites work

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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Identification of a family of human F-box proteins

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Temporal and spatial control of cyclin B1 destruction in metaphase

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Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A.

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Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

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7 January 2021

Direct Binding of CDC20 Protein Family Members Activates the Anaphase-Promoting Complex in Mitosis and G1

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7 January 2021

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

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Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

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7 January 2021

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

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Cyclin is degraded by the ubiquitin pathway

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7 January 2021

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

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7 January 2021

Microinjection of Antibody to Mad2 Protein into Mammalian Cells in Mitosis Induces Premature Anaphase

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7 January 2021

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor.

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7 January 2021

The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells

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7 January 2021

Budding yeast Cdc20: a target of the spindle checkpoint.

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Early events in DNA replication require cyclin E and are blocked by p21CIP1

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The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

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APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle

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Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events

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7 January 2021

Fission Yeast Slp1: An Effector of the Mad2-Dependent Spindle Checkpoint

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7 January 2021

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

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7 January 2021

Regulation of APC activity by phosphorylation and regulatory factors

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7 January 2021

Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family

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7 January 2021

Mitotic regulation of the APC activator proteins CDC20 and CDH1

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7 January 2021

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

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7 January 2021

Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts

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Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis.

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Cyclin synthesis drives the early embryonic cell cycle

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7 January 2021

The anaphase-promoting complex: new subunits and regulators

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Identification of novel F-box proteins in Xenopus laevis

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7 January 2021

Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex

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7 January 2021

Yeast Hct1 Is a Regulator of Clb2 Cyclin Proteolysis

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7 January 2021

The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae

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7 January 2021

Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.

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7 January 2021

The spindle assembly checkpoint in budding yeast

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7 January 2021

Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage

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7 January 2021

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

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7 January 2021

TRIADs: a new class of proteins with a novel cysteine-rich signature

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7 January 2021

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

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7 January 2021

Mad2 transiently associates with an APC/p55Cdc complex during mitosis

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7 January 2021

Identification of a Cullin Homology Region in a Subunit of the Anaphase-Promoting Complex

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7 January 2021

Whose end is destruction: cell division and the anaphase-promoting complex

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7 January 2021

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

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7 January 2021