Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates (Q24300250)

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10 January 2020

title

Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates (English)

1 reference

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Cell division cycle associated 5

10 January 2020

main subject

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protein-containing complex binding

GOA release 2020-03-11

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Cell division cycle associated 5

GOA release 2020-03-11

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GOA release 2020-03-11

author

Susannah Rankin

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15837422%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

author name string

Nagi G Ayad

series ordinal

2

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10 January 2020

Marc W Kirschner

series ordinal

3

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10 January 2020

language of work or name

English

0 references

publication date

1 April 2005

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10 January 2020

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10 January 2020

volume

18

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10 January 2020

issue

2

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10 January 2020

page(s)

185-200

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Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos

10 January 2020

cites work

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A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae

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Pds5 cooperates with cohesin in maintaining sister chromatid cohesion.

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Cohesion between sister chromatids must be established during DNA replication

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Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

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Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins

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Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells

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7 January 2021

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1

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Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation.

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Chromosome cohesion is regulated by a clock gene paralogue TIM-1.

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Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex.

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RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

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Overexpression of bamacan/SMC3 causes transformation

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Cohesin defects lead to premature sister chromatid separation, kinetochore dysfunction, and spindle-assembly checkpoint activation

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7 January 2021

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