Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome (Q27937521)

GOA release 2020-03-11

author name string

Yasushi Saeki

0 references

Tai Kudo

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Takayuki Sone

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Yoshiko Kikuchi

4

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Hideyoshi Yokosawa

5

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Akio Toh-e

6

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Keiji Tanaka

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover

7

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language of work or name

English

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publication date

18 February 2009

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1 reference

1 December 2016

28

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page(s)

359-71

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issue

4

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cites work

1 reference

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Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341

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A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

20 March 2017

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Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant

20 March 2017

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Polyubiquitin chains: polymeric protein signals

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7 April 2017

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Protein regulation by monoubiquitin

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Mammalian 26S proteasomes remain intact during protein degradation

7 April 2017

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Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

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29 September 2017

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29 September 2017

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Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein

2 June 2018

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NPl1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase.

2 June 2018

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2 June 2018

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Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis

21 January 2018

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In vitro assembly and recognition of Lys-63 polyubiquitin chains

21 January 2018

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Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?

21 January 2018

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An unstructured initiation site is required for efficient proteasome-mediated degradation

21 January 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2008.305

Sequential E2s drive polyubiquitin chain assembly on APC targets

21 January 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2008.305

Definitive evidence for Ufd2-catalyzed elongation of the ubiquitin chain through Lys48 linkage

21 January 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2008.305

Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest

21 January 2018

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Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

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Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

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12 December 2020

Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunit 5

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12 December 2020

The tail of a ubiquitin-conjugating enzyme redirects multi-ubiquitin chain synthesis from the lysine 48-linked configuration to a novel nonlysine-linked form

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12 December 2020

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

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12 December 2020

Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity

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12 December 2020

Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site

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12 December 2020

The deubiquitinating enzyme Ubp2 modulates Rsp5-dependent Lys63-linked polyubiquitin conjugates in Saccharomyces cerevisiae

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12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2008.305

1 reference

1582898

1582898

1 reference

1 reference

1 reference