p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum Concept (Q28079390)

International Journal of Molecular Sciences

language of work or name

1 reference

10 November 2016

9 references

19 September 2019

28 November 2019

11 December 2019

14 December 2019

18 December 2019

19 December 2019

20 December 2019

31 July 2022

9 references

19 September 2019

28 November 2019

11 December 2019

14 December 2019

18 December 2019

19 December 2019

20 December 2019

31 July 2022

17

1 reference

issue

11

1 reference

Creative Commons Attribution

copyright license

8 references

19 September 2019

28 November 2019

11 December 2019

14 December 2019

18 December 2019

19 December 2019

20 December 2019

31 July 2022

0 references

Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulators

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Extended string binding mode of the phosphorylated transactivation domain of tumor suppressor p53

20 March 2017

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Classification of intrinsically disordered regions and proteins

20 March 2017

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Uncovering the role of p53 splice variants in human malignancy: a clinical perspective

20 March 2017

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Reversal of the DNA-binding-induced loop L1 conformational switch in an engineered human p53 protein

20 March 2017

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Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism

20 March 2017

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HMGB1-facilitated p53 DNA binding occurs via HMG-Box/p53 transactivation domain interaction, regulated by the acidic tail

20 March 2017

1 reference

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An integrated encyclopedia of DNA elements in the human genome

20 March 2017

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Structure of Human SMYD2 Protein Reveals the Basis of p53 Tumor Suppressor Methylation

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Structure of the p53 Transactivation Domain in Complex with the Nuclear Receptor Coactivator Binding Domain of CREB Binding Protein

20 March 2017

1 reference

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Structure of the p53 C-terminus bound to 14-3-3: implications for stabilization of the p53 tetramer

20 March 2017

1 reference

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Prediction of protein binding regions in disordered proteins

20 March 2017

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Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

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1 reference

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20 March 2017

1 reference

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Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation

20 March 2017

1 reference

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Molecular basis of Pirh2-mediated p53 ubiquitylation

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1 reference

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20 March 2017

1 reference

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Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

20 March 2017

1 reference

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Intrinsically Disordered Proteins in Human Diseases: Introducing the D 2 Concept

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1 reference

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Acetylation is indispensable for p53 activation

20 March 2017

1 reference

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Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex

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1 reference

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Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor

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1 reference

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Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

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1 reference

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Genetic Control of Biochemical Reactions in Neurospora

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Molecular recognition of p53 and MDM2 by USP7/HAUSP

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1 reference

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p53 isoforms can regulate p53 transcriptional activity.

20 March 2017

1 reference

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1 reference

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1 reference

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Regulation of p53 activity through lysine methylation

20 March 2017

1 reference

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Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

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1 reference

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1 reference

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Life in a crowded world

1 reference

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Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

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1 reference

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1 reference

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1 reference

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20 March 2017

1 reference

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Effects of macromolecular crowding on protein folding and aggregation

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1 reference

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

20 March 2017

1 reference

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

20 March 2017

1 reference

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1 reference

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WAF1, a potential mediator of p53 tumor suppression

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1 reference

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20 March 2017

1 reference

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20 March 2017

1 reference

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1 reference

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1 reference

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1 reference

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Intrinsically disordered protein

20 March 2017

1 reference

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Analysis of molecular recognition features (MoRFs)

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1 reference

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Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover

20 March 2017

1 reference

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

20 March 2017

1 reference

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p53 mutations in human cancers

20 March 2017

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

20 March 2017

1 reference

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A decade and a half of protein intrinsic disorder: biology still waits for physics

20 March 2017

1 reference

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The importance of intrinsic disorder for protein phosphorylation

20 March 2017

1 reference

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Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

20 March 2017

1 reference

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Blinded by the Light: The Growing Complexity of p53

20 March 2017

1 reference

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Live or let die: the cell's response to p53

7 April 2017

1 reference

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7 April 2017

1 reference

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7 April 2017

1 reference

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Intrinsic dynamics of an enzyme underlies catalysis

7 April 2017

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IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content

7 April 2017

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Intrinsically unstructured proteins

7 April 2017

1 reference

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Intrinsic disorder and protein function

7 April 2017

1 reference

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Natively unfolded proteins: a point where biology waits for physics

7 April 2017

1 reference

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Coupling of folding and binding for unstructured proteins

7 April 2017

1 reference

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Post-translational modifications and activation of p53 by genotoxic stresses

7 April 2017

1 reference

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Sequence complexity of disordered protein

7 April 2017

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7 April 2017

1 reference

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Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

7 April 2017

1 reference

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DNA damage activates p53 through a phosphorylation-acetylation cascade

7 April 2017

1 reference

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

7 April 2017

1 reference

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Cancer. p53, guardian of the genome

7 April 2017

1 reference

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A draft map of the human proteome

7 April 2017

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Aberrant Splicing in Cancer: Mediators of Malignant Progression through an Imperfect Splice Program Shift

7 April 2017

1 reference

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Role of p53 isoforms and aggregations in cancer

29 September 2017

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Genetic Modifiers of the p53 Pathway

29 September 2017

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29 September 2017

1 reference

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29 September 2017

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29 September 2017

1 reference

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Tetramer formation of tumor suppressor protein p53: Structure, function, and applications

29 September 2017

1 reference

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Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

29 September 2017

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The quest of the human proteome and the missing proteins: digging deeper.

29 September 2017

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An acetyl-methyl switch drives a conformational change in p53.

29 September 2017

1 reference

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Structural plasticity of methyllysine recognition by the tandem tudor domain of 53BP1

29 September 2017

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Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases

29 September 2017

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Introducing protein intrinsic disorder

29 September 2017

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Germline TP53 mutations and the changing landscape of Li-Fraumeni syndrome

29 September 2017

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Mutant TP53 posttranslational modifications: challenges and opportunities.

29 September 2017

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State of the human proteome in 2013 as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology- and disease-driven Human Proteome Project

29 September 2017

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Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology

29 September 2017

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29 September 2017

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Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Proteoform: a single term describing protein complexity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The case for intrinsically disordered proteins playing contributory roles in molecular recognition without a stable 3D structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Unusual biophysics of intrinsically disordered proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The impact of post-transcriptional regulation in the p53 network

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The state of the human proteome in 2012 as viewed through PeptideAtlas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

D²P²: database of disordered protein predictions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Detecting p53 isoforms at protein level

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 isoform profiling in glioblastoma and injured brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Mutant p53: one name, many proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Surf the post-translational modification network of p53 regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 N-terminal phosphorylation: a defining layer of complex regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Alternative splicings on p53, BRCA1 and PTEN genes involved in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 Isoforms: An Intracellular Microprocessor?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Phosphorylation of p53 modifies sensitivity to ionizing radiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Unstructural biology coming of age.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 and its mutants in tumor cell migration and invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 post-translational modification: deregulated in tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 isoforms gain functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Regulation of the p53 pathway by ubiquitin and related proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Archaic chaos: intrinsically disordered proteins in Archaea

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Posttranslational modification of p53: cooperative integrators of function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The isoforms of the p53 protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

TP53 mutations in human cancers: origins, consequences, and clinical use

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Understanding protein non-folding.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

PONDR-FIT: a meta-predictor of intrinsically disordered amino acids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The protein kingdom extended: ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

ANCHOR: web server for predicting protein binding regions in disordered proteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

A unified model of protein dynamics.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Modifications of p53: competing for the lysines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

p53 Oligomerization is essential for its C-terminal lysine acetylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Structural biology of the tumor suppressor p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA-damaging agent cisplatin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Expression levels of p53 and p73 isoforms in stage I and stage III ovarian cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The tetramerization domain of p53 is required for efficient BAK oligomerization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Characterization of molecular recognition features, MoRFs, and their binding partners

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Intrinsic disorder and functional proteomics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Length-dependent prediction of protein intrinsic disorder.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Solution structure of p53 core domain: structural basis for its instability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Role of protein dynamics in reaction rate enhancement by enzymes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Flexible nets. The roles of intrinsic disorder in protein interaction networks.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Exploiting heterogeneous sequence properties improves prediction of protein disorder.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

A human protein atlas for normal and cancer tissues based on antibody proteomics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Post-translational modification of p53 in tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Protein motions promote catalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Protein dynamics and enzymatic catalysis: investigating the peptidyl-prolyl cis-trans isomerization activity of cyclophilin A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Theory of protein folding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Inhibition of the p53-MDM2 interaction: targeting a protein-protein interface.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Protein folding revisited. A polypeptide chain at the folding ? misfolding ? nonfolding cross-roads: which way to go?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Splice mutations in the p53 gene: case report and review of the literature.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Identification and functions of usefully disordered proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Molecular mechanism of the interaction between MDM2 and p53.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Preorganization and protein dynamics in enzyme catalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Assessing TP53 status in human tumours to evaluate clinical outcome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Enzyme dynamics during catalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

What does it mean to be natively unfolded?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Macromolecular crowding: obvious but underappreciated

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The role of tetramerization in p53 function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The p53 tumor suppressor gene: from molecular biology to clinical investigation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

P53 germline mutations in childhood cancers and cancer risk for carrier individuals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Theory of protein folding: the energy landscape perspective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Macromolecular crowding: biochemical, biophysical, and physiological consequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Structural dynamics of liganded myoglobin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

How crowded is the cytoplasm?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The p53 tumour suppressor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Estimation of macromolecule concentrations and excluded volume effects for the cytoplasm of Escherichia coli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Crystallographic studies of the dynamic properties of lysozyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Temperature-dependent X-ray diffraction as a probe of protein structural dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The structural and functional signatures of proteins that undergo multiple events of post-translational modification

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Tissue-specific splicing of disordered segments that embed binding motifs rewires protein interaction networks

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Regulation of p53 isoform expression in renal cell carcinoma

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Finding one's way in proteomics: a protein species nomenclature

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

PrDOS: prediction of disordered protein regions from amino acid sequence

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Expression of p53 isoforms in squamous cell carcinoma of the head and neck

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Influence of excluded volume upon macromolecular structure and associations in 'crowded' media

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Genetic alterations in the p53 gene in the blast crisis of chronic myelogenous leukemia: analysis by polymerase chain reaction based techniques

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Solvent viscosity and protein dynamics

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Dynamics of metmyoglobin crystals investigated by nuclear gamma resonance absorption

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Einfluss der Configuration auf die Wirkung der Enzyme

20 June 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

The protein trinity--linking function and disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Signal transduction via unstructured protein conduits.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Coupled folding and binding with alpha-helix-forming molecular recognition elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Disordered competitive recruiter: fast and foldable.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

A new conceptual framework for enzyme catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Protein folding funnels: the nature of the transition state ensemble

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

ESpritz: accurate and fast prediction of protein disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Calcium-dependent interaction of S100B with the C-terminal domain of the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Alternative splicing of p53 and p73: the novel p53 splice variant p53delta is an independent prognostic marker in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Phosphorylation site interdependence of human p53 post-translational modifications in response to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Li-Fraumeni syndrome in a Turkish family.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

The TP53 mutation, R337H, is associated with Li-Fraumeni and Li-Fraumeni-like syndromes in Brazilian families.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Penetrance of adrenocortical tumours associated with the germline TP53 R337H mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Ratio disruption of the ∆133p53 and TAp53 isoform equilibrium correlates with poor clinical outcome in intrahepatic cholangiocarcinoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Expression of p53 isoforms in renal cell carcinoma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Protein folding mechanisms and the multidimensional folding funnel.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

Protein disorder and the evolution of molecular recognition: theory, predictions and observations.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5133874

27 November 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS17111874

Protein folding: Thickening the broth

21 January 2018

1 reference

12 December 2020

An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors

1 reference

12 December 2020

Intrinsic protein disorder in complete genomes

1 reference

12 December 2020

Two functional assays employed to detect an unusual mutation in the oligomerisation domain of p53 in a Li-Fraumeni like family

1 reference

12 December 2020

Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53

1 reference

12 December 2020

Dynamics of ligand binding to myoglobin

1 reference

12 December 2020

Optimizing long intrinsic disorder predictors with protein evolutionary information

1 reference

12 December 2020

A germline missense mutation R337C in exon 10 of the human p53 gene

1 reference

12 December 2020

Protein kinase CK1 is a p53-threonine 18 kinase which requires prior phosphorylation of serine 15

1 reference

12 December 2020

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

12 December 2020

Distinct pattern of p53 phosphorylation in human tumors

1 reference

12 December 2020

Predicting Protein Disorder for N-, C-, and Internal Regions

1 reference

12 December 2020

Differential recognition of phosphorylated transactivation domains of p53 by different p300 domains

1 reference

12 December 2020

p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products

1 reference

12 December 2020

A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemia

1 reference

12 December 2020