A new conceptual framework for enzyme catalysis (Q30047989)

25 May 2017

2

Nigel S. Scrutton

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25 May 2017

author name string

Michael J. Sutcliffe

series ordinal

1

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25 May 2017

language of work or name

English

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publication date

July 2002

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25 May 2017

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25 May 2017

volume

269

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25 May 2017

issue

13

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25 May 2017

page(s)

3096-3102

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Enzymology takes a quantum leap forward

25 May 2017

cites work

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Effects of protein glycosylation on catalysis: changes in hydrogen tunneling and enthalpy of activation in the glucose oxidase reaction

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Enzymatic H-transfer requires vibration-driven extreme tunneling

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New insights into enzyme catalysis. Ground state tunnelling driven by protein dynamics

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Effect of pressure on deuterium isotope effects of yeast alcohol dehydrogenase: evidence for mechanical models of catalysis.

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Follow the protons: a low-barrier hydrogen bond unifies the mechanisms of the aspartic proteases

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Reductive half-reaction of the H172Q mutant of trimethylamine dehydrogenase: evidence against a carbanion mechanism and assignment of kinetically influential ionizations in the enzyme-substrate complex

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Optimizing the Michaelis complex of trimethylamine dehydrogenase: identification of interactions that perturb the ionization of substrate and facilitate catalysis with trimethylamine base.

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Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate†

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21 January 2018

Identifiers

DOI

1 reference