p53 isoforms gain functions (Q37771862)

22 August 2017

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title

p53 isoforms gain functions (English)

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22 August 2017

V Olivares-Illana

1

1 reference

PubMed ID

20622898

22 August 2017

R Fåhraeus

series ordinal

2

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PubMed ID

20622898

22 August 2017

language of work or name

English

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publication date

12 July 2010

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22 August 2017

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22 August 2017

29

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22 August 2017

5113-5119

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22 August 2017

37

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https://scigraph.springernature.com/pub.10.1038/onc.2010.266

22 August 2017

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cites work

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

31 March 2020

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p53 isoforms can regulate p53 transcriptional activity.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

Oncogene-induced senescence as an initial barrier in lymphoma development

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P53 mRNA controls p53 activity by managing Mdm2 functions

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi

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Tumour biology: senescence in premalignant tumours

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Senescence in tumours: evidence from mice and humans

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Identification and characterization of a novel cell cycle-regulated internal ribosome entry site

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DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53.

31 March 2020

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A DNA damage checkpoint response in telomere-initiated senescence

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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

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Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin.

31 March 2020

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WAF1, a potential mediator of p53 tumor suppression

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Short telomeres limit tumor progression in vivo by inducing senescence

31 March 2020

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Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner

31 March 2020

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Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions

31 March 2020

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p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence

31 March 2020

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Regulation of human p53 activity and cell localization by alternative splicing

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p53 and little brother p53/47: linking IRES activities with protein functions

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The N terminus of the murine p53 tumour suppressor is an independent regulatory domain affecting activation and thermostability

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

31 March 2020

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A microRNA component of the p53 tumour suppressor network

31 March 2020

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14-3-3 proteins in cell cycle regulation

31 March 2020

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14-3-3sigma is a p53-regulated inhibitor of G2/M progression

31 March 2020

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Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

31 March 2020

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Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

31 March 2020

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The Mdm2 and p53 genes are conserved in the Arachnids.

31 March 2020

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IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

31 March 2020

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The first 30 years of p53: growing ever more complex

31 March 2020

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Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling

31 March 2020

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The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes

31 March 2020

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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

31 March 2020

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

A cell cycle-dependent internal ribosome entry site

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

Signal integration in the endoplasmic reticulum unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

ER stress and the unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

The jury is in: p73 is a tumor suppressor after all.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

Regulation of mRNA Translation during cellular division.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

31 March 2020

Surfing the p53 network

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Blinded by the Light: The Growing Complexity of p53

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

Interaction between the retinoblastoma protein and the oncoprotein MDM2

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.266

p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

Identification of a novel p53 functional domain that is necessary for mediating apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

Two internal ribosome entry sites mediate the translation of p53 isoforms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.266

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.266

1 reference

22 August 2017

1 reference

PubMed ID

20622898