Chromatin response to DNA double-strand break damage (Q37961878)

26 August 2017

Chromatin response to DNA double-strand break damage (English)

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26 August 2017

Yunhe Bao

1

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26 August 2017

1 June 2011

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26 August 2017

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26 August 2017

3

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26 August 2017

307-321

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26 August 2017

3

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Crystal structure of the nucleosome core particle at 2.8 A resolution

26 August 2017

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Histone variants, nucleosome assembly and epigenetic inheritance

21 January 2018

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The language of covalent histone modifications

21 January 2018

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Translating the Histone Code

21 January 2018

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Histone modifications in transcriptional regulation

21 January 2018

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Chromatin modifications and their function

21 January 2018

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The language of histone crosstalk

21 January 2018

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The biology of chromatin remodeling complexes

21 January 2018

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A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

21 January 2018

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ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex

21 January 2018

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Histone H2A variants H2AX and H2AZ

21 January 2018

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

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ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

21 January 2018

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ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

21 January 2018

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Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

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Characteristics of gamma-H2AX foci at DNA double-strand breaks sites

21 January 2018

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

21 January 2018

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Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

21 January 2018

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Requirement of the MRN complex for ATM activation by DNA damage

21 January 2018

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

21 January 2018

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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 January 2018

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gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

21 January 2018

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H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

21 January 2018

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

21 January 2018

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INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

21 January 2018

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Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites

21 January 2018

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Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair

21 January 2018

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The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

21 January 2018

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A role for Saccharomyces cerevisiae histone H2A in DNA repair.

21 January 2018

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FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.

21 January 2018

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Contribution of the serine 129 of histone H2A to chromatin structure

21 January 2018

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Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin A.

21 January 2018

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gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

21 January 2018

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A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication

21 January 2018

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A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

21 January 2018

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Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae

21 January 2018

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Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

21 January 2018

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Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions

21 January 2018

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Chromatin disassembly and reassembly during DNA repair.

21 January 2018

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WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

21 January 2018

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Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

21 January 2018

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Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway

21 January 2018

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DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics

21 January 2018

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Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX.

21 January 2018

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H2AX: functional roles and potential applications

21 January 2018

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H2A.Z: view from the top.

21 January 2018

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A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin

21 January 2018

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Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes

21 January 2018

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Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome

21 January 2018

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The highly conserved and multifunctional NuA4 HAT complex

21 January 2018

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Connection between histone H2A variants and chromatin remodeling complexes

21 January 2018

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Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break

21 January 2018

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Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

21 January 2018

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NuA4-dependent acetylation of nucleosomal histones H4 and H2A directly stimulates incorporation of H2A.Z by the SWR1 complex.

21 January 2018

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Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage.

21 January 2018

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Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage

21 January 2018

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The SWR1 histone replacement complex causes genetic instability and genome-wide transcription misregulation in the absence of H2A.Z.

21 January 2018

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Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory

21 January 2018

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Global regulation of H2A.Z localization by the INO80 chromatin-remodeling enzyme is essential for genome integrity

21 January 2018

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NuA4 subunit Yng2 function in intra-S-phase DNA damage response

21 January 2018

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Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

21 January 2018

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Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors.

21 January 2018

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Histone H4 acetylation in Drosophila. Frequency of acetylation at different sites defined by immunolabelling with site-specific antibodies

21 January 2018

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30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction

21 January 2018

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Histone H4-K16 acetylation controls chromatin structure and protein interactions

21 January 2018

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

21 January 2018

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MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair

21 January 2018

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MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1.

21 January 2018

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Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly

21 January 2018

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Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair

21 January 2018

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CBP/p300-mediated acetylation of histone H3 on lysine 56

21 January 2018

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Histone H3-K56 acetylation is important for genomic stability in mammals

21 January 2018

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Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation

21 January 2018

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Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

21 January 2018

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Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

21 January 2018

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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

21 January 2018

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A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

21 January 2018

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Preferential dimethylation of histone H4 lysine 20 by Suv4-20

21 January 2018

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MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

21 January 2018

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Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

21 January 2018

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Heterochromatic genome stability requires regulators of histone H3 K9 methylation

21 January 2018

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HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.

21 January 2018

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Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

21 January 2018

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Drosophila p53 is required to increase the levels of the dKDM4B demethylase after UV-induced DNA damage to demethylate histone H3 lysine 9.

21 January 2018

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Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway

21 January 2018

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Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae.

21 January 2018

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Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae

21 January 2018

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Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4.

21 January 2018

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Phosphorylation of histone H2B at DNA double-strand breaks.

21 January 2018

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Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase

21 January 2018

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The ubiquitous role of ubiquitin in the DNA damage response

21 January 2018

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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

21 January 2018

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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

21 January 2018

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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

21 January 2018

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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

21 January 2018

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Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

21 January 2018

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BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response

21 January 2018

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The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

21 January 2018

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Gene silencing: trans-histone regulatory pathway in chromatin

21 January 2018

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Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8.

21 January 2018

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Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing.

21 January 2018

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Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes.

21 January 2018

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INO80 subfamily of chromatin remodeling complexes.

21 January 2018

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A chromatin remodelling complex involved in transcription and DNA processing.

21 January 2018

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Involvement of actin-related proteins in ATP-dependent chromatin remodeling.

21 January 2018

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Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

21 January 2018

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Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks.

21 January 2018

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The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner

21 January 2018

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Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses

21 January 2018

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Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes

21 January 2018

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A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

21 January 2018

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DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity

21 January 2018

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The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

21 January 2018

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Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair

21 January 2018

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The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks

21 January 2018

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RSC functions as an early double-strand-break sensor in the cell's response to DNA damage

21 January 2018

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The RSC nucleosome-remodeling complex is required for Cohesin's association with chromosome arms.

21 January 2018

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The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion

21 January 2018

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RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin

21 January 2018

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Dual chromatin remodeling roles for RSC during DNA double strand break induction and repair at the yeast MAT locus

21 January 2018

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Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction

21 January 2018

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A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair

21 January 2018

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The human Mi-2/NuRD complex and gene regulation

21 January 2018

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The Mi-2/NuRD complex: a critical epigenetic regulator of hematopoietic development, differentiation and cancer.

21 January 2018

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21 January 2018

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The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage

21 January 2018

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The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage

21 January 2018

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Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

21 January 2018

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A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

21 January 2018

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ATM mediated phosphorylation of CHD4 contributes to genome maintenance

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/EPI.11.14

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26 August 2017

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PubMed ID

22122340