The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. (Q27934025)

PubMed

15632126

1 December 2016

title

The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. (English)

1 reference

PubMed

E2 ubiquitin-conjugating protein RAD6 YGL058W

1 December 2016

0 references

1 reference

E3 ubiquitin-protein ligase BRE1 YDL074C

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

protein ubiquitination

1 reference

Federico Lazzaro

2

0 references

Michele Giannattasio

object named as

Michele Giannattasio

series ordinal

1

0 references

Marco Muzi-Falconi

object named as

Marco Muzi-Falconi

series ordinal

4

0 references

Paolo Plevani

object named as

Paolo Plevani

series ordinal

3

0 references

publication date

18 March 2005

0 references

language of work or name

English

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published in

1 reference

PubMed

15632126

Cell cycle checkpoints: preventing an identity crisis

1 December 2016

volume

280

0 references

issue

11

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page(s)

9879-86

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cites work

1 reference

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Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

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The MRN complex: coordinating and mediating the response to broken chromosomes

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Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway

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When repair meets chromatin. First in series on chromatin dynamics

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LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae

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Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae

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Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

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The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

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Rad53 FHA Domain Associated with Phosphorylated Rad9 in the DNA Damage Checkpoint

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Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase.

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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Interplay between chromatin and cell cycle checkpoints in the context of ATR/ATM-dependent checkpoints

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Histone H2A variants H2AX and H2AZ

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DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

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A role for Saccharomyces cerevisiae histone H2A in DNA repair.

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Rad6-dependent ubiquitination of histone H2B in yeast

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H2B ubiquitylation: the end is in sight

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Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

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DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae

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The Ubiquitin-Conjugating Enzyme Rad6 (Ubc2) Is Required for Silencing in Saccharomyces cerevisiae

21 January 2018

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The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme

21 January 2018

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Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions

21 January 2018

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Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites

21 January 2018

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Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter

21 January 2018

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A conserved RING finger protein required for histone H2B monoubiquitination and cell size control.

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21 January 2018

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Yeast pip3/mec3 mutants fail to delay entry into S phase and to slow DNA replication in response to DNA damage, and they define a functional link between Mec3 and DNA primase

21 January 2018

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Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

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Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

21 January 2018

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Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

21 January 2018

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Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes.

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H2AX: the histone guardian of the genome

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RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

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Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation

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Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint

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Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest.

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Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

21 January 2018

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Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

21 January 2018

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Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M414453200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

15632126

1 reference

Consolidated OpenCitations Corpus – April 2017