Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies (Q37426436)

20 August 2017

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Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies (English)

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20 August 2017

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Jochen Kieninger

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Agnes Görlach

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object named as

Agnes Görlach

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Thomas A Gorr

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Peter Ebbesen

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Kaye Williams

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Ludwig Dubois

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Claudiu T Supuran

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Silvia Pastorekova

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Erik O Pettersen

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Gerhard Jobst

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Roland H Wenger

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Philippe Lambin

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Twan Van Den Beucken

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Lorenz Poellinger

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Arvydas Kanopka

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Max Gasmann

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Patrick Maxwell

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1 April 2009

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Journal of Enzyme Inhibition and Medicinal Chemistry

20 August 2017

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24 Suppl 1

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20 August 2017

1-39

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The histological structure of some human lung cancers and the possible implications for radiotherapy

20 August 2017

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https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Functional cellular assays with multiparametric silicon sensor chips

21 January 2018

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https://api.crossref.org/works/10.1080%2F14756360902784425

Pericellular oxygen depletion during ordinary tissue culturing, measured with oxygen microsensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of angiogenesis by hypoxia: role of the HIF system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Expanding chemical biology of 2-oxoglutarate oxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Oxygen sensing by HIF hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

An endoplasmic reticulum transmembrane prolyl 4-hydroxylase is induced by hypoxia and acts on hypoxia-inducible factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

JunD reduces tumor angiogenesis by protecting cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The increase in pulmonary arterial pressure caused by hypoxia depends on iron status

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Endogenous 2-oxoacids differentially regulate expression of oxygen sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Understanding alternative splicing: towards a cellular code

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The structure and function of proteins involved in mammalian pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Pre-mRNA splicing and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The connection between splicing and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Alterations of pre-mRNA splicing in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Aberrant and alternative splicing in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mechanism for elimination of a tumor suppressor: aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Identification of alternative spliced variants of human hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Targeting hypoxia tolerance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Exploiting tumour hypoxia in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Biological consequences of tumor hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia signalling through mTOR and the unfolded protein response in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-induced energy stress regulates mRNA translation and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Response of U87 glioma xenografts treated with concurrent rapamycin and fractionated radiotherapy: possible role for thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The hypoxic proteome is influenced by gene-specific changes in mRNA translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of Cited2 expression provides a functional link between translational and transcriptional responses during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reactive species: a cell damaging rout assisting to chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Models of reactive oxygen species in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Deficiency of manganese superoxide dismutase in hepatocytes disrupts zonated gene expression in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mitochondria and reactive oxygen species in renal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mitochondrial DNA in human malignancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Redox signaling through NADPH oxidases: involvement in vascular proliferation and coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Protein tyrosine phosphatases: from genes, to function, to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mechanisms of ROS modulated cell survival during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

NADPH oxidases in the gastrointestinal tract: a potential role of Nox1 in innate immune response and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Redox signaling in angiogenesis: role of NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reactive oxygen species as mediators of signal transduction in ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

NOX enzymes as novel targets for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reactive oxygen species in phagocytic leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Molecular links between tumor angiogenesis and inflammation: inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

NOX5 variants are functionally active in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia in cancer cell metabolism and pH regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Lactate: mirror and motor of tumor malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Causes and consequences of tumour acidity and implications for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Microenvironmental and cellular consequences of altered blood flow in tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of tumor pH and the role of carbonic anhydrase 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Cancer-associated carbonic anhydrases and their inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Activating transcription factor 4 is translationally regulated by hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Counteraction of pRb-dependent protection after extreme hypoxia by elevated ribonucleotide reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

p21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Cell inactivation and cell cycle inhibition as induced by extreme hypoxia: the possible role of cell cycle arrest as a protection against hypoxia-induced lethal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of cell proliferation under extreme and moderate hypoxia: the role of pyrimidine (deoxy)nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of the cyclin E gene by transcription factor E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Fast control of DNA replication in response to hypoxia and to inhibited protein synthesis in CCRF-CEM and HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reduction of Ribonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Structure and function of the radical enzyme ribonucleotide reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Ribonucleotide reductase inhibitors: new strategies for cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Metabolic depression in animals: physiological perspectives and biochemical generalizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Sensing and responding to hypoxia via HIF in model invertebrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The Pasteur effect in facultative anaerobic metazoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Oxygen deprivation causes suspended animation in the zebrafish embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Dephosphorylation of cell cycle-regulated proteins correlates with anoxia-induced suspended animation in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Inhibition of cell-cycle progression by acute treatment with various degrees of hypoxia: modifications induced by low concentrations of misonidazole present during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Metabolic depression: a response of cancer cells to hypoxia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxic Stress Proteins: Survival of the Fittest

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

A reduction in the in situ rates of oxygen and glucose consumption of cells in EMT6/Ro spheroids during growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Role of oxygen vs. glucose in energy metabolism in a mammary carcinoma perfused ex vivo: direct measurement by 31P NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Metabolic imaging in multicellular spheroids of oncogene-transfected fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Phosphorous metabolites and steady-state energetics of transformed fibroblasts during three-dimensional growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Radiobiological characteristics of solid tumours depending on the p53 status of the tumour cells, with emphasis on the response of intratumour quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Inhibition of 4E-BP1 sensitizes U87 glioblastoma xenograft tumors to irradiation by decreasing hypoxia tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia requires notch signaling to maintain the undifferentiated cell state

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Cancer genes and the pathways they control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-induced genetic instability--a calculated mechanism underlying tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia and defective apoptosis drive genomic instability and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia, gene expression, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxic regulation of metastasis via hypoxia-inducible factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mechanisms of disease: angiogenesis in urologic malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia in prostate cancer: a powerful shield against tumour destruction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF-1 and tumour radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Significance of HIF-1-active cells in angiogenesis and radioresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia as a target for combined modality treatments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tissue oxygen distribution in head and neck cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase IX expression and tumor oxygenation status do not correlate at the microregional level in locally advanced cancers of the uterine cervix

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Lack of correlation between expression of HIF-1alpha protein and oxygenation status in identical tissue areas of squamous cell carcinomas of the uterine cervix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Gene expression profiling of human cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Genetic expression profiles and biologic pathway alterations in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Gene profiling in squamous cell carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Predicting a local recurrence after breast-conserving therapy by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

hsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tumor Hypoxia and Heterogeneity: Challenges and Opportunities for the Future

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Optical sensor-based oxygen tension measurements correspond with hypoxia marker binding in three human tumor xenograft lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Semiquantitative immunohistochemical analysis for hypoxia in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The maximum uptake of (18)F-deoxyglucose on positron emission tomography scan correlates with survival, hypoxia inducible factor-1alpha and GLUT-1 in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Impact of supervised gene signatures of early hypoxia on patient survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Molecular (functional) imaging for radiotherapy applications: an RTOG symposium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Beyond detection: novel applications for PET imaging to guide cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Assessment of hypoxia in experimental mice tumours by [18F]fluoromisonidazole PET and pO2 electrode measurements. Influence of tumour volume and carbogen breathing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

[18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography in response evaluation after chemo-/radiotherapy of non-small-cell lung cancer: a feasibility study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Evaluation of hypoxia in an experimental rat tumour model by [(18)F]fluoromisonidazole PET and immunohistochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia and glucose metabolism in malignant tumors: evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-imaging with (18)F-Misonidazole and PET: changes of kinetics during radiotherapy of head-and-neck cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

PET imaging with hypoxia tracers: a must in radiation therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

A model of reoxygenation dynamics of head-and-neck tumors based on serial 18F-fluoromisonidazole positron emission tomography investigations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

21 January 2018

Tumor hypoxia imaging

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

[18F]EF3 is not superior to [18F]FMISO for PET-based hypoxia evaluation as measured in a rat rhabdomyosarcoma tumour model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Pharmacokinetics of the hypoxic cell cytotoxic agent tirapazamine and its major bioreductive metabolites in mice and humans: retrospective analysis of a pharmacokinetically guided dose-escalation strategy in a phase I trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Advances in methods for assessing tumor hypoxia in vivo: implications for treatment planning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Development of small molecule carbonic anhydrase IX inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Biodistribution and pharmacokinetics of 125I-labeled monoclonal antibody M75 specific for carbonic anhydrase IX, an intrinsic marker of hypoxia, in nude mice xenografted with human colorectal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: a phase I trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The hypoxic tumor cell: a target for selective cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Preclinical studies of porfiromycin as an adjunct to radiotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Concurrent chemo-radiotherapy with mitomycin C compared with porfiromycin in squamous cell cancer of the head and neck: final results of a randomized clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Pharmacological approach towards the development of indolequinone bioreductive drugs based on the clinically inactive agent EO9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Phase I/II pilot study of intravesical apaziquone (EO9) for superficial bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Safety and side effects of immediate instillation of apaziquone following transurethral resection in patients with nonmuscle invasive bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Combining bioreductive drugs and radiation for the treatment of solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Overexpression of human NADPH:cytochrome c (P450) reductase confers enhanced sensitivity to both tirapazamine (SR 4233) and RSU 1069

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference to in vivo methods of evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tumor microenvironment and the response to anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Tirapazamine administered as a neoadjuvant to radiotherapy reduces metastatic dissemination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia targeted gene therapy to increase the efficacy of tirapazamine as an adjuvant to radiotherapy: reversing tumor radioresistance and effecting cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Bioreductive drugs: from concept to clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

iNOS as a therapeutic target for treatment of human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reductive heme-dependent activation of the n-oxide prodrug AQ4N by nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Enhancement of the anti-tumour effect of cyclophosphamide by the bioreductive drugs AQ4N and tirapazamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The chemopotentiation of cisplatin by the novel bioreductive drug AQ4N

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase I study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: a substudy of Trans-Tasman Radiation O

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Schedule-dependent potentiation of chemotherapeutic drugs by the bioreductive compounds NLCQ-1 and tirapazamine against EMT6 tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Therapeutic advantage from combining paclitaxel with the hypoxia-selective cytotoxin NLCQ-1 in murine tumor- or human xenograft-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Dissecting the role of multiple reductases in bioactivation and cytotoxicity of the antitumor agent 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone (RH1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase IX: a new druggable target for the design of antitumor agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Fluorescence- and spin-labeled carbonic anhydrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrases: current state of the art, therapeutic applications and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic anhydrase IX: historical and future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

G250: a carbonic anhydrase IX monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Transcriptional responses to intermittent hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Reactive oxygen species and cellular oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Cancer cell killing via ROS: to increase or decrease, that is the question

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Spatially resolved biologic information from in vivo EPRI, OMRI, and MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

New potentiomentric dissolved oxygen sensors in thick film technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Lactate Dehydrogenase 5 Expression in Operable Colorectal Cancer: Strong Association With Survival and Activated Vascular Endothelial Growth Factor Pathway—A Report of the Tumour Angiogenesis Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

The relative importance of NADPH: cytochrome c (P450) reductase for determining the sensitivity of human tumour cells to the indolequinone EO9 and related analogues lacking functionality at the C-2 and C-3 positions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Carbonic Anhydrase Inhibitors: Hypoxia-Activatable Sulfonamides Incorporating Disulfide Bonds that Target the Tumor-Associated Isoform IX†

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14756360902784425

Quiescent S-phase cells as indicators of extreme physiological conditions in human tumor xenografts

21 January 2018

1 reference

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Protein turnover during metabolic arrest in turtle hepatocytes: role and energy dependence of proteolysis

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The respiration of ascites tumour cells at low oxygen concentrations

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Superoxide and nitric oxide--participation in cell communication

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Potential bioreductive alkylating agents. 1. Benzoquinone derivatives

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Mitochondria: oxygen sinks rather than sensors?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Effect of some proliferative and environmental factors on the toxicity of mitomycin C to tumor cells in vitro

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

RSU 1069, a nitroimidazole containing an aziridine group. Bioreduction greatly increases cytotoxicity under hypoxic conditions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Oxygen effects in radiobiology

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Hypoxic cell sensitizers for radiotherapy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Antimalarial activities of polyhydroxyphenyl and hydroxamic acid derivatives

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Factors affecting sensitivity to EO9 in rodent and human tumour cells in vitro: DT-diaphorase activity and hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Reductive Metabolism of the Nitroimidazole-Based Hypoxia-Selective Cytotoxin NLCQ-1 (NSC 709257)

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Synergistic enhancement of the antitumor effect of taxol by the bioreductive compound NLCQ-1, in vivo: comparison with tirapazamine

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

The Role of NAD(P)H: Quinone Reductase (EC 1.6.99.2, DT-Diaphorase) in the Reductive Bioactivation of the Novel Indoloquinone Antitumor Agent E09

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Characterization of radiolabeled fluoromisonidazole as a probe for hypoxic cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

HYDRATED ELECTRONS AND RADIOBIOLOGICAL SENSITISATION

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Influence of the hypoxic subvolume on the survival of patients with head and neck cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Rates of oxygen consumption for proliferating and quiescent cells isolated from multicellular tumor spheroids.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Retinal degeneration in rats induced by CI-1010, a 2-nitroimidazole radiosensitizer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Continuous recording of blood oxygen tensions by polarography

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Induction of tumour hypoxia post-irradiation: a method for increasing the sensitizing efficiency of misonidazole and RSU 1069 in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Hypoxia-induced pRB hypophosphorylation results from downregulation of CDK and upregulation of PP1 activities

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

A toxicity and pharmacokinetic study in man of the hypoxic-cell radiosensitiser RSU-1069

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

The retinoblastoma gene product is reversibly dephosphorylated and bound in the nucleus in S and G2 phases during hypoxic stress

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Hypoxia inhibits G1/S transition through regulation of p27 expression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Rat cytochromes P450 (CYP) specifically contribute to the reductive bioactivation of AQ4N, an alkylaminoanthraquinone-di-N-oxide anticancer prodrug

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/14756360902784425

Identifiers

DOI

10.1080/14756360902784425

1 reference

20 August 2017

1 reference