Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system (Q33247514)

24 July 2017

Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system (English)

1 reference

24 July 2017

1 reference

1 reference

Daniel P Stiehl

1

0 references

author name string

Renato Wirthner

2

1 reference

24 July 2017

Jens Köditz

3

1 reference

24 July 2017

Patrick Spielmann

4

1 reference

24 July 2017

Gieri Camenisch

5

1 reference

24 July 2017

Roland H Wenger

6

1 reference

24 July 2017

language of work or name

English

0 references

publication date

21 June 2006

1 reference

Journal of Biological Chemistry

24 July 2017

1 reference

24 July 2017

281

1 reference

24 July 2017

33

1 reference

24 July 2017

23482-23491

1 reference

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

24 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

A nonradioactive 96-well plate assay for the detection of hypoxia-inducible factor prolyl hydroxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Induction of the von Hippel-Lindau tumor suppressor gene by late hypoxia limits HIF-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Accumulation of hypoxia-inducible factor-1alpha is limited by transcription-dependent depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Mapping, characterization, and expression analysis of the SM-20 human homologue, c1orf12, and identification of a novel related gene, SCAND2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Mammalian EGLN genes have distinct patterns of mRNA expression and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601719200

21 January 2018

Identifiers

DOI

10.1074/JBC.M601719200

1 reference

24 July 2017

1 reference