DNA damage-induced nuclear factor-kappa B activation and its roles in cancer progression (Q88337377)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

title

DNA damage-induced nuclear factor-kappa B activation and its roles in cancer progression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

author name string

Wei Wang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Arul M Mani

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Zhao-Hui Wu

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

publication date

27 March 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

page(s)

45-59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1

23 March 2020

cites work

1 reference

12 December 2020

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

1 reference

12 December 2020

Structural Basis for Recognition of Diubiquitins by NEMO

1 reference

12 December 2020

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

1 reference

12 December 2020

Autophosphorylation and ATM activation: additional sites add to the complexity

1 reference

12 December 2020

ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks

1 reference

12 December 2020

A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB.

1 reference

12 December 2020

Role of DNA-PK in the cellular response to DNA double-strand breaks

1 reference

12 December 2020

Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer

1 reference

12 December 2020

The cellular response to general and programmed DNA double strand breaks

1 reference

12 December 2020

The ATM protein is required for sustained activation of NF-kappaB following DNA damage.

1 reference

12 December 2020

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

1 reference

12 December 2020

Metastamirs: a stepping stone towards improved cancer management

1 reference

12 December 2020

Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation

1 reference

12 December 2020

NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699.

1 reference

12 December 2020

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation

1 reference

12 December 2020

Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells

1 reference

12 December 2020

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

1 reference

12 December 2020

The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM.

1 reference

12 December 2020

A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

1 reference

12 December 2020

Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation

1 reference

12 December 2020

A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones

1 reference

12 December 2020

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

1 reference

12 December 2020

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

1 reference

12 December 2020

Primary immunodeficiencies associated with DNA-repair disorders

1 reference

12 December 2020

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

1 reference

12 December 2020

Inhibition of poly(ADP-ribose) polymerase in cancer

1 reference

12 December 2020

Many faces of NF-kappaB signaling induced by genotoxic stress

1 reference

12 December 2020

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

1 reference

12 December 2020

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

1 reference

12 December 2020

Return to homeostasis: downregulation of NF-κB responses

1 reference

12 December 2020

Involvement of novel autophosphorylation sites in ATM activation

1 reference

12 December 2020

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

1 reference

12 December 2020

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

1 reference

12 December 2020

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

1 reference

12 December 2020

Immunity, Inflammation, and Cancer

1 reference

12 December 2020

DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes

1 reference

12 December 2020

p50 (NF-κB1) is an effector protein in the cytotoxic response to DNA methylation damage

1 reference

12 December 2020

TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: implications for a replication restart-based mechanism for ATR checkpoint activation

1 reference

12 December 2020

PIDD mediates NF-kappaB activation in response to DNA damage

1 reference

12 December 2020

NF-kappa B as a target for cancer therapy

1 reference

12 December 2020

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

12 December 2020

DNA instability at chromosomal fragile sites in cancer

1 reference

12 December 2020

The DNA-dependent protein kinase (DNA-PK): More than just a case of making ends meet?

1 reference

12 December 2020

ATR: a master conductor of cellular responses to DNA replication stress

1 reference

12 December 2020

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

12 December 2020

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

1 reference

12 December 2020

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

1 reference

12 December 2020

Regulation and function of NF-kappaB transcription factors in the immune system

1 reference

12 December 2020

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more

1 reference

12 December 2020

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

12 December 2020

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

1 reference

12 December 2020

The ATR pathway: fine-tuning the fork

1 reference

12 December 2020

cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation

1 reference

12 December 2020

Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathways

1 reference

12 December 2020

Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit

1 reference

12 December 2020

High-resolution profiling of histone methylations in the human genome

1 reference

12 December 2020

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

1 reference

12 December 2020

Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 1986. 46: 705-716

1 reference

12 December 2020

The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death

1 reference

12 December 2020

Parallel profiling of the transcriptome, cistrome, and epigenome in the cellular response to ionizing radiation

1 reference

12 December 2020

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

12 December 2020

Autoregulation of I kappa B alpha activity

1 reference

12 December 2020

Hallmarks of Cancer: The Next Generation

1 reference

12 December 2020

SUMO-specific proteases: a twist in the tail

1 reference

12 December 2020

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1 reference

12 December 2020

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

1 reference

12 December 2020

NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway

1 reference

12 December 2020

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

1 reference

12 December 2020

TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase

1 reference

12 December 2020

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction

1 reference

12 December 2020

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

1 reference

12 December 2020

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

1 reference

12 December 2020

The DNA damage response: implications for tumor responses to radiation and chemotherapy

1 reference

12 December 2020

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

12 December 2020

MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling

1 reference

12 December 2020

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

1 reference

12 December 2020

A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages

1 reference

12 December 2020

A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation

1 reference

12 December 2020

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

1 reference

12 December 2020

DNA damage induces NF-κB-dependent microRNA-21 up-regulation and promotes breast cancer cell invasion

1 reference

12 December 2020

The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

1 reference

12 December 2020

ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia

1 reference

12 December 2020

DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity

1 reference

12 December 2020

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

12 December 2020

ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress

1 reference

12 December 2020

Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer

1 reference

12 December 2020

NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress.

1 reference

12 December 2020

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

1 reference

12 December 2020

PARP inhibition: PARP1 and beyond

1 reference

12 December 2020

PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress.

1 reference

12 December 2020

A microRNA component of the p53 tumour suppressor network

1 reference

12 December 2020

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

1 reference

12 December 2020

Endogenous DNA damage in humans: a review of quantitative data

1 reference

12 December 2020

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

1 reference

12 December 2020

Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA

1 reference

12 December 2020

NF-kappaB as a therapeutic target in cancer

1 reference

12 December 2020

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

1 reference

12 December 2020

The role of poly(ADP-ribose) in the DNA damage signaling network

1 reference

12 December 2020

A ubiquitin ligase complex assembles linear polyubiquitin chains

1 reference

12 December 2020

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

1 reference

12 December 2020

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

1 reference

12 December 2020

Molecular organization of the presynaptic active zone

1 reference

12 December 2020

Good cop, bad cop: the different faces of NF-kappaB

1 reference

12 December 2020

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

12 December 2020

Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistance

1 reference

12 December 2020

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

1 reference

12 December 2020

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

12 December 2020

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

1 reference

12 December 2020

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

1 reference

12 December 2020

NF-kappaB p65-dependent transactivation of miRNA genes following Cryptosporidium parvum infection stimulates epithelial cell immune responses

1 reference

12 December 2020

Nuclear localisation of nuclear factor-kappaB transcription factors in prostate cancer: an immunohistochemical study

1 reference

12 December 2020

Living on a break: cellular senescence as a DNA-damage response

1 reference

12 December 2020

Maintaining genome stability at the replication fork

1 reference

12 December 2020

MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target

1 reference

12 December 2020

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

1 reference

12 December 2020

Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue

1 reference

12 December 2020

TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.

1 reference

12 December 2020

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks

1 reference

12 December 2020

A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

1 reference

12 December 2020

Regulation of homologous recombination by RNF20-dependent H2B ubiquitination.

1 reference

12 December 2020

Targeting DNA Repair in Cancer: Beyond PARP Inhibitors.

1 reference

12 December 2020

Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair

1 reference

12 December 2020

SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia

1 reference

12 December 2020

Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation

1 reference

12 December 2020

NF-kappaB and IKK as therapeutic targets in cancer

1 reference

12 December 2020

Active roles for inhibitory kappaB kinases alpha and beta in nuclear factor-kappaB-mediated chemoresistance to doxorubicin

1 reference

12 December 2020

Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis

1 reference

12 December 2020

Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer

1 reference

12 December 2020

IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation

1 reference

12 December 2020

The impact of heterochromatin on DSB repair

1 reference

12 December 2020

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

1 reference

12 December 2020

Choosing the right path: does DNA-PK help make the decision?

1 reference

12 December 2020

Poly(ADP-Ribose) polymerase inhibition: "targeted" therapy for triple-negative breast cancer

1 reference

12 December 2020

DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out.

1 reference

12 December 2020

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

12 December 2020

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together

1 reference

12 December 2020

Alkylating agents induce activation of NFkappaB in multiple myeloma cells

1 reference

12 December 2020

Autoregulatory feedback loops terminating the NF-kappaB response

1 reference

12 December 2020

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

1 reference

12 December 2020

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

12 December 2020

The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer

1 reference

12 December 2020

Nuclear factor-kappaB: the enemy within

1 reference

12 December 2020

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

1 reference

12 December 2020

Chromatin structure analyses identify miRNA promoters

1 reference

12 December 2020

The microcosmos of cancer

1 reference

12 December 2020

USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO

1 reference

12 December 2020

Regulatory feedback loop between NF-kappaB and MCP-1-induced protein 1 RNase

1 reference

12 December 2020

Mechanisms of double-strand break repair in somatic mammalian cells

1 reference

12 December 2020

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

12 December 2020

New regulators of NF-kappaB in inflammation

1 reference

12 December 2020

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

1 reference

12 December 2020

Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

1 reference

12 December 2020

The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

1 reference

12 December 2020

TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation

1 reference

12 December 2020

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

1 reference

12 December 2020

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

1 reference

12 December 2020

SN52, a novel nuclear factor-kappaB inhibitor, blocks nuclear import of RelB:p52 dimer and sensitizes prostate cancer cells to ionizing radiation

1 reference

12 December 2020

The DNA Damage Response: Making It Safe to Play with Knives

1 reference

12 December 2020

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

1 reference

12 December 2020

Nuclear retention of ATM at sites of DNA double strand breaks

1 reference

12 December 2020

RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells

1 reference

12 December 2020

The fission yeast spSet1p is a histone H3-K4 methyltransferase that functions in telomere maintenance and DNA repair in an ATM kinase Rad3-dependent pathway

1 reference

12 December 2020

Shared principles in NF-kappaB signaling

1 reference

12 December 2020

S phase dependence and involvement of NF-kappaB activating kinase to NF-kappaB activation by camptothecin

1 reference

12 December 2020

Signaling to NF-kappaB

1 reference

12 December 2020

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

1 reference

12 December 2020

Linear ubiquitination prevents inflammation and regulates immune signalling

1 reference

12 December 2020

Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction

1 reference

12 December 2020

10.20517/2394-4722.2017.03

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28626800%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference