Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase (Q28131711)

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10 January 2020

title

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase (English)

1 reference

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Erratum: Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

10 January 2020

corrigendum / erratum

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author

Thomas Helleday

10

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10 January 2020

Nicola Curtin

9

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10 January 2020

author name string

Helen E Bryant

1

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10 January 2020

Niklas Schultz

2

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10 January 2020

Huw D Thomas

3

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10 January 2020

Kayan M Parker

4

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10 January 2020

Dan Flower

5

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10 January 2020

Elena Lopez

6

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10 January 2020

Suzanne Kyle

7

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10 January 2020

Mark Meuth

8

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10 January 2020

publication date

1 April 2005

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10 January 2020

language of work or name

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10 January 2020

volume

434

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10 January 2020

issue

7035

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10 January 2020

page(s)

913-917

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Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination

10 January 2020

cites work

1 reference

Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro

21 April 2017

1 reference

Cancer susceptibility and the functions of BRCA1 and BRCA2

21 April 2017

1 reference

Instability and decay of the primary structure of DNA

21 April 2017

1 reference

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 April 2017

1 reference

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Loss of poly(ADP-ribose) polymerase-1 causes increased tumour latency in p53-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

PARP is important for genomic stability but dispensable in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Brca2 (XRCC11) Deficiency Results in Radioresistant DNA Synthesis and a Higher Frequency of Spontaneous Deletions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Construction of human XRCC1 minigenes that fully correct the CHO DNA repair mutant EM9

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Poly(ADP‐ribose) polymerase activity in nucleotide permeable cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Direct stimulation of poly(ADP ribose) polymerase in permeabilized cells by double-stranded DNA oligomers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

RAD51 is involved in repair of damage associated with DNA replication in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03443

7 January 2021

Identifiers

DOI

10.1038/NATURE03443

2 references

Consolidated OpenCitations Corpus – April 2017

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Dimensions publication ID

10 January 2020

1036499081

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017