De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling (Q24299573)

TNF alpha induced protein 3

GOA release 2020-03-11

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protein K63-linked ubiquitination

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

1 reference

12

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Aravind L Iyer

object named as

L Aravind

5

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Christian Wiesmann

object named as

Christian Wiesmann

8

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author name string

Ingrid E Wertz

1

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Karen M O'Rourke

2

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Honglin Zhou

3

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Michael Eby

4

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Somasekar Seshagiri

6

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Ping Wu

7

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Rohan Baker

9

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David L Boone

10

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Averil Ma

11

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Vishva M Dixit

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

13

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publication date

5 August 2004

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language of work or name

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430

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issue

7000

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page(s)

694-9

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cites work

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Mechanisms underlying ubiquitination

20 April 2017

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Themes and variations on ubiquitylation

20 April 2017

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Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

20 April 2017

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

20 April 2017

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Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

20 April 2017

1 reference

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

20 April 2017

1 reference

Otubains: a new family of cysteine proteases in the ubiquitin pathway

20 April 2017

1 reference

A novel type of deubiquitinating enzyme

20 April 2017

1 reference

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity

20 April 2017

1 reference

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

20 April 2017

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

20 April 2017

1 reference

Signal transduction: aspirin, ubiquitin and cancer

20 April 2017

1 reference

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

20 April 2017

1 reference

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

20 April 2017

1 reference

The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

20 April 2017

1 reference

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02794

NF-kappaB signaling. Many roads lead to madrid

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02794

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The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

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Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons

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LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2

1 reference

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Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02794

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Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

1 reference

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Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

1 reference

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The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02794

7 January 2021

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

1 reference

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7 January 2021