Return to homeostasis: downregulation of NF-κB responses (Q37902868)

25 August 2017

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title

Return to homeostasis: downregulation of NF-κB responses (English)

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25 August 2017

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Jürgen Ruland

1

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PubMed ID

21772279

25 August 2017

language of work or name

English

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publication date

19 June 2011

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25 August 2017

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25 August 2017

12

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25 August 2017

8

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25 August 2017

709-714

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https://scigraph.springernature.com/pub.10.1038/ni.2055

25 August 2017

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cites work

Inflammation and oncogenesis: a vicious connection

1 reference

The nuclear factor NF-kappaB pathway in inflammation

21 January 2018

1 reference

Oncogenic activation of NF-kappaB.

21 January 2018

1 reference

Shared principles in NF-kappaB signaling

21 January 2018

1 reference

Regulation and function of NF-kappaB transcription factors in the immune system

21 January 2018

1 reference

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

21 January 2018

1 reference

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

21 January 2018

1 reference

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

1 reference

IkappaBepsilon provides negative feedback to control NF-kappaB oscillations, signaling dynamics, and inflammatory gene expression.

21 January 2018

1 reference

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

21 January 2018

1 reference

IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response

21 January 2018

1 reference

IkappaBbeta is an essential co-activator for LPS-induced IL-1beta transcription in vivo.

21 January 2018

1 reference

IkappaB family members function by different mechanisms

21 January 2018

1 reference

Duration of nuclear NF-kappaB action regulated by reversible acetylation

21 January 2018

1 reference

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

21 January 2018

1 reference

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

21 January 2018

1 reference

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 January 2018

1 reference

Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

21 January 2018

1 reference

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes

21 January 2018

1 reference

Signaling to NF-kappaB: regulation by ubiquitination

21 January 2018

1 reference

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

1 reference

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

1 reference

A20: from ubiquitin editing to tumour suppression

21 January 2018

1 reference

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

1 reference

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB

21 January 2018

1 reference

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

21 January 2018

1 reference

A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

21 January 2018

1 reference

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

21 January 2018

1 reference

The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20

21 January 2018

1 reference

Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling

21 January 2018

1 reference

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins

21 January 2018

1 reference

NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling

21 January 2018

1 reference

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

1 reference

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes

21 January 2018

1 reference

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

21 January 2018

1 reference

Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation

21 January 2018

1 reference

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

21 January 2018

1 reference

MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression.

21 January 2018

1 reference

IRAK-M is a negative regulator of Toll-like receptor signaling

21 January 2018

1 reference

Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients

21 January 2018

1 reference

Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia model

21 January 2018

1 reference

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

21 January 2018

1 reference

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.

21 January 2018

1 reference

Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10

21 January 2018

1 reference

Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival

21 January 2018

1 reference

PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity.

21 January 2018

1 reference

Negative regulation of NF-kappaB signaling by PIAS1.

21 January 2018

1 reference

Control of specificity and magnitude of NF-kappa B and STAT1-mediated gene activation through PIASy and PIAS1 cooperation

21 January 2018

1 reference

Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity.

21 January 2018

1 reference

Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

21 January 2018

1 reference

Nuclear ubiquitin ligases, NF-kappaB degradation, and the control of inflammation

21 January 2018

1 reference

PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

21 January 2018

1 reference

COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

21 January 2018

1 reference

Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit

21 January 2018

1 reference

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

21 January 2018

1 reference

A fourth IkappaB protein within the NF-kappaB signaling module

21 January 2018

1 reference

Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation

21 January 2018

1 reference

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 January 2018

1 reference

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

21 January 2018

1 reference

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

1 reference

Rescue of TRAF3-null mice by p100 NF-kappa B deficiency

21 January 2018

1 reference

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

21 January 2018

1 reference

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation

21 January 2018

1 reference

The NF-kappaB family of transcription factors and its regulation

21 January 2018

1 reference

MicroRNAs: new regulators of immune cell development and function

21 January 2018

1 reference

MicroRNAs: the fine-tuners of Toll-like receptor signalling

21 January 2018

1 reference

NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

21 January 2018

1 reference

MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells

21 January 2018

1 reference

Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation

21 January 2018

1 reference

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma

21 January 2018

1 reference

NFKBIA deletion in glioblastomas

21 January 2018

1 reference

Frequent inactivation of A20 in B-cell lymphomas

21 January 2018

1 reference

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

21 January 2018

1 reference

Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells

21 January 2018

1 reference

Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

21 January 2018

1 reference

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

21 January 2018

1 reference

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

21 January 2018

1 reference

IRAK-M is involved in the pathogenesis of early-onset persistent asthma

21 January 2018

1 reference

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

21 January 2018

1 reference

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

21 January 2018

1 reference

Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation

21 January 2018

1 reference

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

21 January 2018

1 reference

SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772279

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21772279

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.2055

1 reference

PubMed ID

21772279

Dimensions Publication ID

25 August 2017

0 references

1 reference

PubMed ID

21772279