Signal transduction in the type I interferon system and viral countermeasures (Q57077884)

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4 May 2020

title

Signal transduction in the type I interferon system and viral countermeasures (English)

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4 May 2020

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Krzysztof Brzózka

1

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4 May 2020

Christian Pfaller

series ordinal

2

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4 May 2020

Karl-Klaus Conzelmann

series ordinal

3

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4 May 2020

publication date

2 February 2007

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4 May 2020

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4 May 2020

volume

7

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4 May 2020

issue

1

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4 May 2020

page(s)

5-19

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Approaching the asymptote? Evolution and revolution in immunology

4 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

TRAF3: a new regulator of type I interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

Fascination with 2-5A-Dependent RNase: A Unique Enzyme That Functions in Interferon Action*

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

Antiviral response in pandemic influenza viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FSITA.200600115

Interferon, double-stranded RNA, and protein phosphorylation

21 January 2018

1 reference

12 December 2020

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

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12 December 2020

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

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12 December 2020

Adenovirus virus-associated RNA and translation control

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12 December 2020

Increased sensitivity of cell-free protein synthesis to double-stranded RNA after interferon treatment

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12 December 2020

Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes

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12 December 2020

Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity

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12 December 2020

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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12 December 2020

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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12 December 2020

Immune defence in mice lacking type I and/or type II interferon receptors

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12 December 2020

Effects of adenovirus E1A protein on interferon-signaling

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12 December 2020

Regulation of the double-stranded RNA-dependent protein kinase PKR by RNAs encoded by a repeated sequence in the Epstein-Barr virus genome

1 reference

12 December 2020

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

1 reference

12 December 2020

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

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12 December 2020

How cells respond to interferons

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12 December 2020

Direct suppression of Stat1 function during adenoviral infection

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12 December 2020

Structure and function of the interferon-beta enhanceosome

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12 December 2020

The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha

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12 December 2020

PKR; a sentinel kinase for cellular stress

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12 December 2020

The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation

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12 December 2020

Bovine respiratory syncytial virus nonstructural proteins NS1 and NS2 cooperatively antagonize alpha/beta interferon-induced antiviral response

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12 December 2020

The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral effects of IFN.

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12 December 2020

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

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12 December 2020

A Toll-like receptor recognizes bacterial DNA

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12 December 2020

Immune response in Stat2 knockout mice

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12 December 2020

HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators

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12 December 2020

Antiviral actions of interferons

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12 December 2020

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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12 December 2020

Virus-induced interferon alpha production by a dendritic cell subset in the absence of feedback signaling in vivo

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12 December 2020

Respiratory syncytial virus (RSV) nonstructural (NS) proteins as host range determinants: a chimeric bovine RSV with NS genes from human RSV is attenuated in interferon-competent bovine cells

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12 December 2020

All four Sendai Virus C proteins bind Stat1, but only the larger forms also induce its mono-ubiquitination and degradation

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12 December 2020

STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replication

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12 December 2020

Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity

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12 December 2020

Innate recognition of bacteria by a macrophage cytosolic surveillance pathway

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12 December 2020

Natural interferon-alpha producing cells: the plasmacytoid dendritic cells.

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12 December 2020

Paramyxovirus strategies for evading the interferon response

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12 December 2020

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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12 December 2020

IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3.

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12 December 2020

Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNAS

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12 December 2020

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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12 December 2020

Triggering the interferon antiviral response through an IKK-related pathway

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12 December 2020

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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12 December 2020

Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3

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12 December 2020

Newcastle disease virus V protein is a determinant of host range restriction

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12 December 2020

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

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12 December 2020

The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

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12 December 2020

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

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12 December 2020

Suppressors of cytokine signaling and immunity

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12 December 2020

Kaposi's sarcoma-associated herpesvirus-encoded vIRF-3 stimulates the transcriptional activity of cellular IRF-3 and IRF-7.

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12 December 2020

Role for bovine viral diarrhea virus Erns glycoprotein in the control of activation of beta interferon by double-stranded RNA

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12 December 2020

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

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12 December 2020

Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation

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12 December 2020

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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12 December 2020

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

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12 December 2020

Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]

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12 December 2020

Measles: immune suppression and immune responses

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12 December 2020

The immunobiology of the TLR9 subfamily

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12 December 2020

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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12 December 2020

Inhibition of nuclear factor kappaB activity by viral interferon regulatory factor 3 of Kaposi's sarcoma-associated herpesvirus.

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12 December 2020

Toll-like receptor signalling

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12 December 2020

Accessory genes of the paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as a focus of active investigation by reverse genetics

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12 December 2020

Functions of toll-like receptors: lessons from KO mice

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12 December 2020

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

1 reference

12 December 2020

Relationships and host range of human, canine, simian and porcine isolates of simian virus 5 (parainfluenza virus 5).

1 reference

12 December 2020

A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter

1 reference

12 December 2020

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

1 reference

12 December 2020

Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier

1 reference

12 December 2020

Plasmacytoid dendritic cells in immunity

1 reference

12 December 2020

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

1 reference

12 December 2020

Thogoto virus ML protein suppresses IRF3 function

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12 December 2020

Weapons of STAT destruction. Interferon evasion by paramyxovirus V protein

1 reference

12 December 2020

Inverse interference: how viruses fight the interferon system

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12 December 2020

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

1 reference

12 December 2020

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

1 reference

12 December 2020

Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3

1 reference

12 December 2020

Role of cyclophilin B in activation of interferon regulatory factor-3.

1 reference

12 December 2020

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

1 reference

12 December 2020

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

1 reference

12 December 2020

Inhibition of toll-like receptor 7- and 9-mediated alpha/beta interferon production in human plasmacytoid dendritic cells by respiratory syncytial virus and measles virus

1 reference

12 December 2020

Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells

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12 December 2020

Mechanisms of type-I- and type-II-interferon-mediated signalling

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12 December 2020

A cytomegaloviral protein reveals a dual role for STAT2 in IFN-{gamma} signaling and antiviral responses

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12 December 2020

Loss of interferon regulatory factor 3 in cells infected with classical swine fever virus involves the N-terminal protease, Npro

1 reference

12 December 2020

Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3.

1 reference

12 December 2020

Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 confers efficient viral replication

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12 December 2020

Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness

1 reference

12 December 2020

Interferon regulatory factor 7 is negatively regulated by the Epstein-Barr virus immediate-early gene, BZLF-1

1 reference

12 December 2020

Cell type-specific involvement of RIG-I in antiviral response

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12 December 2020

Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain.

1 reference

12 December 2020

Regulation of gene-activation pathways by PIAS proteins in the immune system

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12 December 2020

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 reference

12 December 2020

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

1 reference

12 December 2020

VISA is an adapter protein required for virus-triggered IFN-beta signaling

1 reference

12 December 2020

Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1.

1 reference

12 December 2020

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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12 December 2020

Respiratory syncytial virus nonstructural protein 2 specifically inhibits type I interferon signal transduction.

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12 December 2020

Rabies virus P protein interacts with STAT1 and inhibits interferon signal transduction pathways

1 reference

12 December 2020

SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways

1 reference

12 December 2020

Evasion of innate immunity by vaccinia virus

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12 December 2020

Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses

1 reference

12 December 2020

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

1 reference

12 December 2020

Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

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12 December 2020

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

1 reference

12 December 2020

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

12 December 2020

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

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12 December 2020

Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells

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12 December 2020

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

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12 December 2020

Innate immune recognition of viral infection

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12 December 2020

Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA.

1 reference

12 December 2020

Tumor selective replication of Newcastle disease virus: association with defects of tumor cells in antiviral defence

1 reference

12 December 2020

A human cytomegalovirus antagonist of type I IFN-dependent signal transducer and activator of transcription signaling

1 reference

12 December 2020

Inhibition of interferon signaling by rabies virus phosphoprotein P: activation-dependent binding of STAT1 and STAT2.

1 reference

12 December 2020

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection

1 reference

12 December 2020

IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9

1 reference

12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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12 December 2020

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

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12 December 2020

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

1 reference

12 December 2020

Type 1 interferons and the virus-host relationship: a lesson in détente .

1 reference

12 December 2020

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation

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12 December 2020

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

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12 December 2020

Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

1 reference

12 December 2020

The specific and essential role of MAVS in antiviral innate immune responses

1 reference

12 December 2020

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

1 reference

12 December 2020

Reverse genetic generation of recombinant Zaire Ebola viruses containing disrupted IRF-3 inhibitory domains results in attenuated virus growth in vitro and higher levels of IRF-3 activation without inhibiting viral transcription or replication

1 reference

12 December 2020

Essential role of IPS-1 in innate immune responses against RNA viruses

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12 December 2020

Replication of bovine respiratory syncytial virus in murine cells depends on type I interferon-receptor functionality

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12 December 2020

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

1 reference

12 December 2020

Antiviral defense: interferons and beyond

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12 December 2020

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

1 reference

12 December 2020

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

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12 December 2020

EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN.

1 reference

12 December 2020

The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal Degradation

1 reference

12 December 2020

The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I- and TBK-1-directed interferon responses

1 reference

12 December 2020

Complex modulation of cell type-specific signaling in response to type I interferons

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12 December 2020

Suppression of proinflammatory signal transduction and gene expression by the dual nucleic acid binding domains of the vaccinia virus E3L proteins

1 reference

12 December 2020

RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2

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12 December 2020

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

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12 December 2020

5'-Triphosphate RNA is the ligand for RIG-I

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12 December 2020

mda-5, but not RIG-I, is a common target for paramyxovirus V proteins.

1 reference

12 December 2020

GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists

1 reference

12 December 2020

Identifiers

DOI

10.1002/SITA.200600115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32327963%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

1 reference