Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7 (Q24295641)

GOA release 2020-03-11

Toll-like receptor 7

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GOA release 2020-03-11

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9

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Veit Hornung

1

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Gunther Hartmann

Gunther Hartmann

12

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Martin Schlee

5

Martin Schlee

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Stefan Endres

11

Stefan Endres

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Andrea Ablasser

4

Andrea Ablasser

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author name string

Margit Guenthner-Biller

2

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Carole Bourquin

3

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Satoshi Uematsu

6

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Anne Noronha

7

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Muthiah Manoharan

8

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Antonin de Fougerolles

10

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publication date

March 2005

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language of work or name

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11

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issue

3

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page(s)

263-70

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7 January 2021

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

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Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy

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RNA-dependent RNA polymerases, viruses, and RNA silencing

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RNA silencing: the genome's immune system

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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7 January 2021

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

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Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

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7 January 2021

Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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7 January 2021

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7 January 2021

CpG motifs in bacterial DNA trigger direct B-cell activation

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7 January 2021

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

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7 January 2021

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

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7 January 2021

A Toll-like receptor recognizes bacterial DNA

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7 January 2021

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

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7 January 2021

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

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7 January 2021

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

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7 January 2021

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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7 January 2021

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

1 reference

7 January 2021

Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

1 reference

7 January 2021

Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus

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7 January 2021

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

1 reference

7 January 2021

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

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7 January 2021

RNA interference is mediated by 21- and 22-nucleotide RNAs

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7 January 2021

Mechanism and function of a newly identified CpG DNA motif in human primary B cells

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7 January 2021

Recognition of single-stranded RNA viruses by Toll-like receptor 7

1 reference

7 January 2021

CpG-A Oligonucleotides Induce a Monocyte-Derived Dendritic Cell-Like Phenotype That Preferentially Activates CD8 T Cells

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7 January 2021

CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro

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7 January 2021

Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help

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7 January 2021

Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs

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7 January 2021

CpG motifs: the active ingredient in bacterial extracts?

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7 January 2021

Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy

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7 January 2021

Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model

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7 January 2021

Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA.

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7 January 2021

Hepatic diseases--hitting the target with inhibitory RNAs

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7 January 2021

Activation of the interferon system by short-interfering RNAs

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7 January 2021

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

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7 January 2021

Exogenous siRNA mediates sequence-independent gene suppression by signaling through toll-like receptor 3.

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7 January 2021

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

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7 January 2021

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

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7 January 2021

Vaccination with plasmid DNA activates dendritic cells via Toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice

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7 January 2021

Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells

1 reference

7 January 2021