Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining (Q38982117)

8 September 2017

Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining (English)

1 reference

8 September 2017

4

Tasuku Honjo

1 reference

8 September 2017

Andre Stanlie

1

1 reference

8 September 2017

Ashraf S Yousif

series ordinal

2

1 reference

8 September 2017

Hideo Akiyama

series ordinal

3

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8 September 2017

Nasim A Begum

series ordinal

5

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8 September 2017

19 June 2014

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8 September 2017

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8 September 2017

55

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8 September 2017

97-110

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8 September 2017

1

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DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

8 September 2017

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Regulation of DNA damage responses by ubiquitin and SUMO.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

C --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylases

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Loss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Purification of proteins associated with specific genomic Loci

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Histone marks: repairing DNA breaks within the context of chromatin

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

End-joining, translocations and cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

BET domain co-regulators in obesity, inflammation and cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Diversity among memory B cells: origin, consequences, and utility.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

53BP1 facilitates long-range DNA end-joining during V(D)J recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

IgH class switching and translocations use a robust non-classical end-joining pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Genetic dissection of vertebrate 53BP1: a major role in non-homologous end joining of DNA double strand breaks

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Chromatin dynamics and the preservation of genetic information

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Selective inhibition of BET bromodomains

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

DNA repair pathways as targets for cancer therapy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Association of the Mediator complex with enhancers of active genes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

A role for the RNA pol II-associated PAF complex in AID-induced immune diversification

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.MOLCEL.2014.05.018

Identifiers

DOI

10.1016/J.MOLCEL.2014.05.018

1 reference

8 September 2017

1 reference