Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch (Q40522938)

21 September 2017

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch (English)

1 reference

21 September 2017

9

Rudolf Jaenisch

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Tasuku Honjo

10

object named as

Tasuku Honjo

1 reference

21 September 2017

4

Masamichi Muramatsu

1 reference

21 September 2017

8

Laurie A Boyer

1 reference

21 September 2017

7

Detlev Biniszkiewicz

1 reference

21 September 2017

Nasim A Begum

1

1 reference

21 September 2017

Kazuo Kinoshita

2

1 reference

21 September 2017

Naoki Kakazu

3

1 reference

21 September 2017

Hitoshi Nagaoka

5

1 reference

21 September 2017

Reiko Shinkura

6

1 reference

21 September 2017

language of work or name

English

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publication date

1 August 2004

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21 September 2017

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21 September 2017

305

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21 September 2017

1160-1163

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21 September 2017

5687

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Genomic instability in mice lacking histone H2AX

21 September 2017

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Molecular mechanisms of apolipoprotein B mRNA editing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

DNA-dependent protein kinase activity is not required for immunoglobulin class switching

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

AID: how does it aid antibody diversity?

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Separate domains of AID are required for somatic hypermutation and class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Transcription-coupled events associating with immunoglobulin switch region chromatin

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1098444

Identifiers

DOI

10.1126/SCIENCE.1098444

1 reference

21 September 2017

0 references

1 reference