DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation (Q57198273)

5

0 references

Klaus Rajewsky

5

object named as

K Rajewsky

0 references

author name string

Linda Bross

1

0 references

Yosho Fukita

2

0 references

Fraser McBlane

3

0 references

Corinne Démollière

4

0 references

L Bross

1

0 references

Y Fukita

2

0 references

F McBlane

3

0 references

C Démollière

4

0 references

H Jacobs

Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.

6

0 references

language of work or name

English

0 references

publication date

November 2000

0 references

published in

Immunity

0 references

volume

13

0 references

page(s)

589-597

0 references

589-97

0 references

issue

5

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Maturation of the immune response in germinal centers

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Splinkerettes--improved vectorettes for greater efficiency in PCR walking.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Targeting and subsequent selection of somatic hypermutations in the human V kappa repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Intraclonal generation of antibody mutants in germinal centres

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Simplified mammalian DNA isolation procedure

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

A novel cytidine deaminase affects antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

1 reference

7 January 2021

Somatic hypermutation: how many mechanisms diversify V region sequences?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Both DNA strands of antibody genes are hypermutation targets

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Introduction: what mechanism(s) drive hypermutation?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Somatic hypermutation in 5' flanking regions of heavy chain antibody variable regions.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Natural occurrence and origin of somatically mutated memory B cells in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

The role of clonal selection and somatic mutation in autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Progress in understanding the mechanism and consequences of somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Somatic hypermutation, transcription, and DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900059-5

7 January 2021