53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. (Q29465548)

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27 December 2019

title

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination (English)

1 reference

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Transformation related protein 53 binding protein 1

27 December 2019

main subject

DNA damage

0 references

1 reference

GOA release 2020-03-11

author

Julio C Morales

2

1 reference

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27 December 2019

author name string

John P Manis

1

1 reference

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27 December 2019

Zhenfang Xia

3

1 reference

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27 December 2019

Jeffery L Kutok

4

1 reference

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27 December 2019

Frederick W Alt

5

1 reference

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27 December 2019

Phillip B Carpenter

6

2 references

18 April 2017

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27 December 2019

publication date

11 April 2004

1 reference

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27 December 2019

language of work or name

0 references

1 reference

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27 December 2019

volume

5

1 reference

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27 December 2019

issue

5

1 reference

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27 December 2019

page(s)

481-487

1 reference

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Chromosomal stability and the DNA double-stranded break connection

27 December 2019

cites work

1 reference

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

21 April 2017

1 reference

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

21 April 2017

1 reference

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 April 2017

1 reference

Immunity through DNA deamination

21 April 2017

1 reference

The DNA damage response: putting checkpoints in perspective

21 April 2017

1 reference

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

21 April 2017

1 reference

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

21 April 2017

1 reference

AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching

21 April 2017

1 reference

Genomic instability in mice lacking histone H2AX

21 April 2017

1 reference

Cell cycle checkpoint signaling through the ATM and ATR kinases

21 April 2017

1 reference

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

21 April 2017

1 reference

The role of DNA breaks in genomic instability and tumorigenesis

22 May 2017

1 reference

7 January 2021

Sensing and repairing DNA double-strand breaks

1 reference

7 January 2021

The mechanism and regulation of chromosomal V(D)J recombination

1 reference

7 January 2021

Mechanism and control of class-switch recombination

1 reference

7 January 2021

Unraveling V(D)J recombination; insights into gene regulation

1 reference

7 January 2021

Immunoglobulin genes: generating diversity with AID and UNG.

1 reference

7 January 2021

Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity

1 reference

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

7 January 2021

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

7 January 2021

The generation of antibody diversity through somatic hypermutation and class switch recombination

1 reference

7 January 2021

The function of AID in somatic mutation and class switch recombination: upstream or downstream of DNA breaks

1 reference

7 January 2021

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

1 reference

7 January 2021

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

1 reference

7 January 2021

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

1 reference

7 January 2021

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

1 reference

7 January 2021

Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability

1 reference

7 January 2021

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

1 reference

7 January 2021

DNA rearrangement can account for in vitro switching to IgG1.

1 reference

7 January 2021

Structure and expression of germ line immunoglobulin gamma 2b transcripts

1 reference

7 January 2021

Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism

1 reference

7 January 2021

B cell differentiation and isotype switching is related to division cycle number

1 reference

7 January 2021

Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice

1 reference

7 January 2021

Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA.

1 reference

7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

1 reference

7 January 2021

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

7 January 2021

DNA-dependent protein kinase activity is not required for immunoglobulin class switching

1 reference

7 January 2021

Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions

1 reference

7 January 2021

53BP1, a mediator of the DNA damage checkpoint

1 reference

7 January 2021

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

1 reference

7 January 2021

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

1 reference

7 January 2021

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

7 January 2021

The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

1 reference

7 January 2021

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

1 reference

7 January 2021

B cell receptor signal strength determines B cell fate

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI1067

2 references

Consolidated OpenCitations Corpus – April 2017

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27 December 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017