The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation. (Q38507330)

3 September 2017

2 references

19 January 2021

The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc

13 May 2020

main subject

1 reference

ChEBI release 2020-05-28

1 reference

19 January 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

13 May 2020

2

Kirsten Sandvig

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

27 May 2015

2 references

3 September 2017

19 January 2021

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

13 May 2020

19 January 2021

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

13 May 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

13 May 2020

page(s)

9816-9846

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

Creative Commons Attribution

13 May 2020

copyright license

1 reference

19 January 2021

0 references

Intracellular Aspects of the Process of Protein Synthesis

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Urban planning of the endoplasmic reticulum (ER): how diverse mechanisms segregate the many functions of the ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Roles of N-linked glycans in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Protein N-glycosylation: molecular genetics and functional significance

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

ER stress and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Quality control in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Structural requirements of N-glycosylation of proteins. Studies with proline peptides as conformational probes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Conformational implications of asparagine-linked glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

N-glycan structure dictates extension of protein folding or onset of disposal

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Getting in and out from calnexin/calreticulin cycles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Malectin: A Novel Carbohydrate-binding Protein of the Endoplasmic Reticulum and a Candidate Player in the Early Steps of Protein N-Glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Malectin participates in a backup glycoprotein quality control pathway in the mammalian ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Protein folding in a specialized compartment: the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Role of N-oligosaccharide endoplasmic reticulum processing reactions in glycoprotein folding and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The Structure of calnexin, an ER chaperone involved in quality control of protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

NMR structures of 36 and 73-residue fragments of the calreticulin P-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

N-linked sugar-regulated protein folding and quality control in the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

ERp57 is a multifunctional thiol-disulfide oxidoreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Interaction of the thiol-dependent reductase ERp57 with nascent glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Chaperone selection during glycoprotein translocation into the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The number and location of glycans on influenza hemagglutinin determine folding and association with calnexin and calreticulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Molecular and structural basis for N-glycan-dependent determination of glycoprotein fates in cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Substrate-specific requirements for UGT1-dependent release from calnexin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Promotion of transferrin folding by cyclic interactions with calnexin and calreticulin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Reglucosylation of N-linked glycans is critical for calnexin assembly with T cell receptor (TCR) alpha proteins but not TCRbeta proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The UDP-glucose:glycoprotein glucosyltransferase is organized in at least two tightly bound domains from yeast to mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Structural insight into substrate recognition by the endoplasmic reticulum folding-sensor enzyme: crystal structure of third thioredoxin-like domain of UDP-glucose:glycoprotein glucosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Redox-dependent domain rearrangement of protein disulfide isomerase coupled with exposure of its substrate-binding hydrophobic surface

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

UDP-Glc:glycoprotein glucosyltransferase recognizes structured and solvent accessible hydrophobic patches in molten globule-like folding intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Minor folding defects trigger local modification of glycoproteins by the ER folding sensor GT

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Dissecting glycoprotein quality control in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Structure and function of Class I alpha 1,2-mannosidases involved in glycoprotein synthesis and endoplasmic reticulum quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A window of opportunity: timing protein degradation by trimming of sugars and ubiquitins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Family 47 alpha-mannosidases in N-glycan processing

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The lectin ERGIC-53 is a cargo transport receptor for glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Molecular basis of sugar recognition by the human L-type lectins ERGIC-53, VIPL, and VIP36.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A complex of Pdi1p and the mannosidase Htm1p initiates clearance of unfolded glycoproteins from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Endoplasmic reticulum-associated degradation of mammalian glycoproteins involves sugar chain trimming to Man6-5GlcNAc2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Yos9p detects and targets misfolded glycoproteins for ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Defining the glycan destruction signal for endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Human XTP3-B binds to alpha1-antitrypsin variant null(Hong Kong) via the C-terminal MRH domain in a glycan-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Structural basis for oligosaccharide recognition of misfolded glycoproteins by OS-9 in ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Processing of N-linked glycans during endoplasmic-reticulum-associated degradation of a short-lived variant of ribophorin I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Misfolded proteins traffic from the endoplasmic reticulum (ER) due to ER export signals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Golgi-situated endoplasmic reticulum α-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with γ-COP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A striking quality control subcompartment in Saccharomyces cerevisiae: the endoplasmic reticulum-associated compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Mammalian ER mannosidase I resides in quality control vesicles, where it encounters its glycoprotein substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Glycan regulation of ER-associated degradation through compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Trimming of glucosylated N-glycans by human ER α1,2-mannosidase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

In vitro mannose trimming property of human ER α-1,2 mannosidase I

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Structural and sequence-based classification of glycoside hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Transcriptional and translational control in the Mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Orchestrating the unfolded protein response in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Signalling pathways in the unfolded protein response: development from yeast to mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Quality control in the endoplasmic reticulum protein factory

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A trip to the ER: coping with stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Basal autophagy is involved in the degradation of the ERAD component EDEM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A dual role for EDEM1 in the processing of rod opsin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Tyrosinase degradation is prevented when EDEM1 lacks the intrinsically disordered region

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Glycosylation-independent ERAD pathway serves as a backup system under ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Characterization of early EDEM1 protein maturation events and their functional implications

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Role of the endoplasmic reticulum-associated degradation (ERAD) pathway in degradation of hepatitis C virus envelope proteins and production of virus particles

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Sec61p is part of the endoplasmic reticulum-associated degradation machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

A membrane protein required for dislocation of misfolded proteins from the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Derlin-1 and p97/valosin-containing protein mediate the endoplasmic reticulum-associated degradation of human V2 vasopressin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Role of Derlin-1 protein in proteostasis regulation of ATP-sensitive potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Splicing of intron 3 of human BACE requires the flanking introns 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Oligosaccharide modification in the early secretory pathway directs the selection of a misfolded glycoprotein for degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Alpha(1)-antitrypsin deficiency, liver disease and emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Mechanism of action of the toxic lectins abrin and ricin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Reductive activation of ricin and ricin A-chain immunotoxins by protein disulfide isomerase and thioredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Structure of ricin B-chain at 2.5 A resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Dislocation of ricin toxin A chains in human cells utilizes selective cellular factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 {degrees}C

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Quality control of integral membrane proteins by assembly-dependent membrane integration

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Aggresomes: a cellular response to misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Dissecting the ER-associated degradation of a misfolded polytopic membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Glycoproteins form mixed disulphides with oxidoreductases during folding in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES20069816

Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol

21 January 2018

1 reference

12 December 2020

Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi

1 reference

12 December 2020

The specificity of the yeast and human class I ER alpha 1,2-mannosidases involved in ER quality control is not as strict previously reported

1 reference

12 December 2020

A time-dependent phase shift in the mammalian unfolded protein response

1 reference

12 December 2020

The endoplasmic reticulum glucosyltransferase recognizes nearly native glycoprotein folding intermediates

1 reference

12 December 2020

The ER function BiP is a master regulator of ER function

1 reference

12 December 2020

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

12 December 2020

Calnexin, calreticulin and the folding of glycoproteins

1 reference

12 December 2020

The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein

1 reference

12 December 2020

SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane.

1 reference

12 December 2020

The endoplasmic reticulum crossroads for newly synthesized polypeptide chains

1 reference

12 December 2020

A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation

1 reference

12 December 2020

ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase.

1 reference

12 December 2020

Molecular cloning of the high affinity calcium-binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum.

1 reference

12 December 2020

RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes

1 reference

12 December 2020

A frameshift mutation results in a truncated alpha 1-antitrypsin that is retained within the rough endoplasmic reticulum

1 reference

12 December 2020

The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.

1 reference

12 December 2020

The Pi system-inherited variants of serum alpha 1-antitrypsin

1 reference

12 December 2020

Point mutations in the hydrophobic C-terminal region of ricin A chain indicate that Pro250 plays a key role in membrane translocation

1 reference

12 December 2020

Purification to homogeneity of UDP-glucose:glycoprotein glucosyltransferase from Schizosaccharomyces pombe and apparent absence of the enzyme fro Saccharomyces cerevisiae

1 reference

12 December 2020

Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane

1 reference

12 December 2020

Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin

1 reference

12 December 2020

Calreticulin and calnexin interact with different protein and glycan determinants during the assembly of MHC class I

1 reference

12 December 2020

10.3390/MOLECULES20069816

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272441&resulttype=core&format=json