Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator (Q24299501)

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author name string

J Michael Younger

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Liling Chen

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Hong-Yu Ren

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Meredith F N Rosser

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Emma L Turnbull

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Chun-Yang Fan

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Douglas M Cyr

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

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publication date

11 August 2006

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language of work or name

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126

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issue

3

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page(s)

571-82

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cites work

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Association of domains within the cystic fibrosis transmembrane conductance regulator

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

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A membrane protein required for dislocation of misfolded proteins from the ER

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Cystic fibrosis problem probed by proteolysis

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Limited proteolysis as a probe for arrested conformational maturation of delta F508 CFTR

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The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR.

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Cotranslational Ubiquitination of Cystic Fibrosis Transmembrane Conductance Regulator in Vitro

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