A dual role for EDEM1 in the processing of rod opsin (Q24320047)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19934218%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

A dual role for EDEM1 in the processing of rod opsin (English)

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12 February 2020

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GOA release 2020-03-11

author

Michael E. Cheetham

5

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12 February 2020

Pere Garriga Sole

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ORCID Public Data File 2021

author name string

Maria Kosmaoglou

1

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12 February 2020

Naheed Kanuga

2

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12 February 2020

Mònica Aguilà

3

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12 February 2020

Pere Garriga

4

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12 February 2020

language of work or name

English

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publication date

24 November 2009

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12 February 2020

published in

Journal of Cell Science

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12 February 2020

volume

122

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12 February 2020

issue

Pt 24

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12 February 2020

page(s)

4465-4472

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describes a project that uses

12 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2787460/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex

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EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites

19 March 2017

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Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

19 March 2017

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A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

19 March 2017

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Rhodopsin mutations responsible for autosomal dominant retinitis pigmentosa. Clustering of functional classes along the polypeptide chain

19 March 2017

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Mechanisms of cell death in rhodopsin retinitis pigmentosa: implications for therapy

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EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin

19 March 2017

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EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin

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IRE1 signaling affects cell fate during the unfolded protein response

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Pharmacological manipulation of gain-of-function and dominant-negative mechanisms in rhodopsin retinitis pigmentosa.

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Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities

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1 reference

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EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.

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Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

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27 September 2017

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Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.

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The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation.

27 September 2017

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Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa

27 September 2017

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27 September 2017

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Structural coupling of 11-cis-7-methyl-retinal and amino acids at the ligand binding pocket of rhodopsin

30 May 2018

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Calnexin is not essential for mammalian rod opsin biogenesis

29 November 2018

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29 November 2018

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Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H.

29 November 2018

1 reference

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A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

29 November 2018

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29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19934218

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.055228

2 references

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release_az4fvzkfqfg2bixnn3g4kmtbme

12 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/az4fvzkfqfg2bixnn3g4kmtbme

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19934218%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2 references