Molecular pathways: BRAF induces bioenergetic adaptation by attenuating oxidative phosphorylation (Q33560698)

28 July 2017

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title

Molecular pathways: BRAF induces bioenergetic adaptation by attenuating oxidative phosphorylation (English)

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28 July 2017

1 reference

Hans R Widlund

3

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David E. Fisher

series ordinal

2

object named as

David E Fisher

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28 July 2017

Rizwan Haq

1

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28 July 2017

language of work or name

English

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publication date

7 March 2014

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28 July 2017

published in

Clinical Cancer Research

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28 July 2017

volume

20

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28 July 2017

issue

9

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28 July 2017

page(s)

2257-2263

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Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma

28 July 2017

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21 June 2018

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21 June 2018

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Importance of glycolysis and oxidative phosphorylation in advanced melanoma

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia

21 June 2018

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A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

21 June 2018

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Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases

21 June 2018

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21 June 2018

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21 June 2018

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A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

21 June 2018

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21 June 2018

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BRAF mutations in hairy-cell leukemia

21 June 2018

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

21 June 2018

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21 June 2018

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

21 June 2018

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21 June 2018

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21 June 2018

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Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation

21 June 2018

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

21 June 2018

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BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells

21 June 2018

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Depletion of mitochondrial DNA by ethidium bromide treatment inhibits the proliferation and tumorigenesis of T47D human breast cancer cells

21 June 2018

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Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum

21 June 2018

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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 June 2018

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 June 2018

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Altered metabolism and mitochondrial genome in prostate cancer

21 June 2018

1 reference

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

B-RAF is a therapeutic target in melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

21 June 2018

1 reference

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On the Origin of Cancer Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

High frequency of BRAF mutations in nevi

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Mutations of the BRAF gene in human cancer

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

21 June 2018

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Loss of PTEN facilitates HIF-1-mediated gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Senescence of human fibroblasts induced by oncogenic Raf.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 June 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 June 2018

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Molecular pathways: regulation of metabolism by RB.

21 June 2018

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BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

31 October 2018

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High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma

31 October 2018

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Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008642

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

31 October 2018

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12 December 2020

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

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12 December 2020

BRAFMutation in Metastatic Colorectal Cancer

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12 December 2020

Effects of mitochondrial gene deletion on tumorigenicity of metastatic melanoma: reassessing the Warburg effect

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12 December 2020

BRAF and RAS mutations in human lung cancer and melanoma

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Suppression of BRAF(V599E) in human melanoma abrogates transformation

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Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer

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12 December 2020

Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells

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12 December 2020

10.1158/1078-0432.CCR-13-0898

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DOI

1 reference

28 July 2017

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28 July 2017

1 reference