Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia (Q35564841)

8 August 2017

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia (English)

1 reference

8 August 2017

1 reference

27

1 reference

8 August 2017

Paul Spagnuolo

14

0 references

Alessandro Datti

Alessandro Datti

16

0 references

Aaron Schimmer

Aaron D Schimmer

29

0 references

John Dick

John E Dick

25

0 references

Connie Eaves

22

Connie J Eaves

1 reference

8 August 2017

12

Yanina Eberhard

1 reference

8 August 2017

7

Rose Hurren

1 reference

8 August 2017

8

Yulia Jitkova

1 reference

8 August 2017

Shrivani Sriskanthadevan

2

Shrivani Sriskanthadevan

1 reference

8 August 2017

3

Bozhena Jhas

1 reference

8 August 2017

Marko Skrtić

1

1 reference

8 August 2017

Marinella Gebbia

4

1 reference

8 August 2017

Xiaoming Wang

5

1 reference

8 August 2017

Zezhou Wang

6

1 reference

8 August 2017

Marcela Gronda

9

1 reference

8 August 2017

Neil Maclean

10

1 reference

8 August 2017

Courteney K Lai

11

1 reference

8 August 2017

Justyna Bartoszko

13

1 reference

8 August 2017

Angela C Rutledge

15

1 reference

8 August 2017

Troy Ketela

17

1 reference

8 August 2017

Jason Moffat

18

1 reference

8 August 2017

Brian H Robinson

19

1 reference

8 August 2017

Jessie H Cameron

20

1 reference

8 August 2017

Jeffery Wrana

21

1 reference

8 August 2017

Mark D Minden

23

1 reference

8 August 2017

Jean C Y Wang

24

1 reference

8 August 2017

Keith Humphries

26

1 reference

8 August 2017

Guri Giaever

28

1 reference

8 August 2017

1 November 2011

1 reference

8 August 2017

1 reference

8 August 2017

20

1 reference

8 August 2017

674-688

1 reference

8 August 2017

5

1 reference

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

8 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Co-translational membrane insertion of mitochondrially encoded proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Comparison of tigecycline penetration into the epithelial lining fluid of infected and uninfected murine lungs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Identification of selective inhibitors of cancer stem cells by high-throughput screening

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Evidence for an active role of IF3mt in the initiation of translation in mammalian mitochondria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

An integrated platform of genomic assays reveals small-molecule bioactivities

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

A single mammalian mitochondrial translation initiation factor functionally replaces two bacterial factors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Modeling the initiation and progression of human acute leukemia in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Energy metabolism in tumor cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Tigecycline: a critical analysis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Functional, biophysical, and structural bases for antibacterial activity of tigecycline

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Pharmacokinetics of Tigecycline after Single and Multiple Doses in Healthy Subjects

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Initiation and elongation factors in mammalian mitochondrial protein biosynthesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Chemogenomic profiling: identifying the functional interactions of small molecules in yeast

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Properties of human mitochondrial ribosomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

On the Origin of Cancer Cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Functional profiling of the Saccharomyces cerevisiae genome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Identification of mammalian mitochondrial translational initiation factor 3 and examination of its role in initiation complex formation with natural mRNAs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Mitochondrial Genome Evolution and the Origin of Eukaryotes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

27 July 2018

Acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Genomic profiling of drug sensitivities via induced haploinsufficiency.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy--the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: final report. European Organiz

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Cooperative and Antagonistic Interactions of Peptidyl-tRNA and Antibiotics with Bacterial Ribosomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Nuclear phospho-Akt increase predicts synergy of PI3K inhibition and doxorubicin in breast and ovarian cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Mitochondrial respiration and membrane potential are regulated by the allosteric ATP-inhibition of cytochrome c oxidase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

A survey of yeast genomic assays for drug and target discovery

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

A novel mitochondrial DNA mutation in COX1 leads to strokes, seizures, and lactic acidosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

An ROS generator, antimycin A, inhibits the growth of HeLa cells via apoptosis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

A unique and universal molecular barcode array

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Mutagenesis of glutamine 290 in Escherichia coli and mitochondrial elongation factor Tu affects interactions with mitochondrial aminoacyl-tRNAs and GTPase activity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

A model of the nuclear control of mitochondrial DNA replication.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221282

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

26 September 2018

1 reference

12 December 2020

Inhibition of mitochondrial protein synthesis promotes increased stability of nuclear-encoded respiratory gene transcripts

1 reference

12 December 2020

Roles of residues in mammalian mitochondrial elongation factor Ts in the interaction with mitochondrial and bacterial elongation factor Tu

1 reference

12 December 2020

Control of cellular proliferation by modulation of oxidative phosphorylation in human and rodent fast-growing tumor cells

1 reference

12 December 2020

10.1016/J.CCR.2011.10.015

Identifiers

DOI

1 reference

8 August 2017

1 reference

8 August 2017

1 reference