Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation (Q34527075)

2 August 2017

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation (English)

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2 August 2017

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Nabeel Bardeesy

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Massimo Loda

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object named as

Massimo Loda

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2 August 2017

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Ronald A DePinho

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2 August 2017

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Sabina Signoretti

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2 August 2017

Manisha Sinha

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2 August 2017

Aram F Hezel

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2 August 2017

Nathaniel A Hathaway

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2 August 2017

Daniel R Carrasco

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2 August 2017

language of work or name

English

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publication date

1 September 2002

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2 August 2017

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2 August 2017

419

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2 August 2017

6903

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2 August 2017

162-167

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https://scigraph.springernature.com/pub.10.1038/nature01045

2 August 2017

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cites work

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Very high risk of cancer in familial Peutz-Jeghers syndrome

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

LKB1 somatic mutations in sporadic tumors

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Cellular senescence: mitotic clock or culture shock?

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Isolation of transformation suppressor genes by cDNA subtraction: lumican suppresses transformation induced by v-src and v-K-ras

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Suppression of anchorage-independent growth and matrigel invasion and delayed tumor formation by elevated expression of fibulin-1D in human fibrosarcoma-derived cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Diminished expression of insulin-like growth factor (IGF) binding protein-5 and activation of IGF-I-mediated autocrine growth in simian virus 40-transformed human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

p8 is critical for tumour development induced by rasV12 mutated protein and E1A oncogene

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

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https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE01045

7 January 2021

Identifiers

DOI

10.1038/NATURE01045

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Dimensions Publication ID

2 August 2017

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