RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites (Q24306486)

Tumor protein p53 binding protein 1

1 reference

Ring finger protein 168

1 reference

Ring finger protein 8

1 reference

protein ubiquitination

1 reference

4

Leah C Young

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Frédérick A Mallette

object named as

Frédérick A Mallette

1

0 references

Michael J. Hendzel

object named as

Michael J Hendzel

5

0 references

Titia Sixma

object named as

Titia K Sixma

7

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author name string

Francesca Mattiroli

2

0 references

Gaofeng Cui

3

0 references

Georges Mer

6

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Stéphane Richard

on focus list of Wikimedia project

8

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language of work or name

English

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publication date

18 April 2012

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published in

The EMBO Journal

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volume

31

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issue

8

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page(s)

1865-78

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ScienceSource

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cites work

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

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Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining

19 March 2017

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HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

19 March 2017

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Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

19 March 2017

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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

19 March 2017

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The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

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Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

19 March 2017

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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

19 March 2017

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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

19 March 2017

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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

19 March 2017

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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

19 March 2017

1 reference

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Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

19 March 2017

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Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

19 March 2017

1 reference

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Tudor, MBT and chromo domains gauge the degree of lysine methylation

19 March 2017

1 reference

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

19 March 2017

1 reference

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JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)

19 March 2017

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Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

19 March 2017

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MDC1 is a mediator of the mammalian DNA damage checkpoint

19 March 2017

1 reference

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

19 March 2017

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19 March 2017

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19 March 2017

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Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

19 March 2017

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Cdc48/p97 mediates UV-dependent turnover of RNA Pol II.

19 March 2017

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MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

19 March 2017

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Histone ubiquitination associates with BRCA1-dependent DNA damage response

19 March 2017

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A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

19 March 2017

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The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

19 March 2017

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MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

19 March 2017

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MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

19 March 2017

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MDC1 is required for the intra-S-phase DNA damage checkpoint

19 March 2017

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19 March 2017

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7 April 2017

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7 April 2017

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SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation.

27 September 2017

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The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein

27 September 2017

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Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.

27 September 2017

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Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice

27 September 2017

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The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

27 September 2017

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27 September 2017

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Preparation of recombinant peptides with site- and degree-specific lysine (13)C-methylation

27 September 2017

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27 September 2017

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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

27 September 2017

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Proteasome function is required for DNA damage response and fanconi anemia pathway activation

27 September 2017

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The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

27 September 2017

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Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343333

Rapid spontaneous accessibility of nucleosomal DNA.

27 September 2017

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Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break

27 September 2017

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53BP1, a mediator of the DNA damage checkpoint

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343333

The site-specific installation of methyl-lysine analogs into recombinant histones

27 September 2017

1 reference

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30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343333

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Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.47

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin

21 January 2018

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Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.47

Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22373579

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Core histone hyperacetylation impacts cooperative behavior and high-affinity binding of histone H1 to chromatin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22373579

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2012.47

1 reference

1 reference

1 reference

PubMed publication ID

22373579

1 reference