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Ring finger protein 168 (Q21127053)

From Wikidata
mammalian protein found in Homo sapiens
  • RNF168
  • ring finger protein 168, E3 ubiquitin protein ligase
  • E3 ubiquitin-protein ligase RNF168
  • RING-type E3 ubiquitin transferase RNF168
  • RING finger protein 168
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    English
    Ring finger protein 168
    mammalian protein found in Homo sapiens
    • RNF168
    • ring finger protein 168, E3 ubiquitin protein ligase
    • E3 ubiquitin-protein ligase RNF168
    • RING-type E3 ubiquitin transferase RNF168
    • RING finger protein 168

    Statements

    molecular function
    ubiquitin-protein transferase activity
    determination method or standard
    IDA
    IEA
    IMP
    8 references
    retrieved
    8 April 2019
    stated in
    53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    cell component
    biological process
    cellular response to DNA damage stimulus
    determination method or standard
    IDA
    IEA
    6 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    Q8IYW5
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
    determination method or standard
    IDA

    Identifiers

     
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