Human p14(Arf): an exquisite sensor of morphological changes and of short-lived perturbations in cell cycle and in nucleolar function (Q44165071)

30 November 2017

Human p14(Arf): an exquisite sensor of morphological changes and of short-lived perturbations in cell cycle and in nucleolar function (English)

1 reference

30 November 2017

Thérèse David-Pfeuty

1

1 reference

PubMed ID

12360404

30 November 2017

Yolande Nouvian-Dooghe

series ordinal

2

1 reference

PubMed ID

12360404

30 November 2017

language of work or name

English

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publication date

1 October 2002

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30 November 2017

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30 November 2017

21

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30 November 2017

6779-6790

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30 November 2017

44

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205871

30 November 2017

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1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Potent inhibitors of cyclin-dependent kinase 2 induce nuclear accumulation of wild-type p53 and nucleolar fragmentation in human untransformed and tumor-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The human protein p19ARF is not detected in hemopoietic human cell lines that abundantly express the alternative beta transcript of the p16INK4a/MTS1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Partially processed pre-rRNA is preserved in association with processing components in nucleolus-derived foci during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The dynamics of postmitotic reassembly of the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Human ARF binds E2F1 and inhibits its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Nucleolar necklaces in chick embryo fibroblast cells. II. Microscope observations of the effect of adenosine analogues on nucleolar necklace formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Checkpoints: controls that ensure the order of cell cycle events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Human ARF protein interacts with topoisomerase I and stimulates its activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Genes involved in senescence and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Regulation of the APC and the exit from mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The Rb/E2F pathway and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

A Restriction Point for Control of Normal Animal Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Nucleolar assembly of the rRNA processing machinery in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Cyclin-dependent kinases govern formation and maintenance of the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

In vivo release of mitotic silencing of ribosomal gene transcription does not give rise to precursor ribosomal RNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Cell-cycle inhibitors: three families united by a common cause

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Cell death: the significance of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

Inhibition of v-Abl transformation by p53 and p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

7 January 2021

Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

7 January 2021

Japan split over US aid for spy satellites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

7 January 2021

Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

7 January 2021

Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

7 January 2021

The labelling index of human and mouse tumours assessed by bromodeoxyuridine staining in vitro and in vivo and flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205871

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205871

1 reference

30 November 2017

1 reference

PubMed ID

12360404