Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells (Q40775811)

23 September 2017

Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells (English)

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23 September 2017

T David-Pfeuty

1

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23 September 2017

Y Nouvian-Dooghe

2

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23 September 2017

V Sirri

3

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23 September 2017

P Roussel

4

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23 September 2017

D Hernandez-Verdun

5

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23 September 2017

language of work or name

English

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publication date

1 September 2001

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23 September 2017

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23 September 2017

20

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23 September 2017

42

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23 September 2017

5951-5963

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204741

23 September 2017

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Regulation of p53 stability

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Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases

21 January 2018

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

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p53 in embryonic development: maintaining a fine balance

21 January 2018

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Potent inhibitors of cyclin-dependent kinase 2 induce nuclear accumulation of wild-type p53 and nucleolar fragmentation in human untransformed and tumor-derived cells

21 January 2018

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Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

21 January 2018

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle

21 January 2018

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The complexity of p53 modulation: emerging patterns from divergent signals

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Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

21 January 2018

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

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Nucleolar necklaces in chick embryo fibroblast cells. I. Formation of necklaces by dichlororibobenzimidazole and other adenosine analogues that decrease RNA synthesis and degrade preribosomes

21 January 2018

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Nucleolar necklaces in chick embryo fibroblast cells. II. Microscope observations of the effect of adenosine analogues on nucleolar necklace formation

21 January 2018

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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Covalent and noncovalent modifiers of the p53 protein

21 January 2018

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p53 regulation by post-translational modification and nuclear retention in response to diverse stresses

21 January 2018

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Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

21 January 2018

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New functional activities for the p21 family of CDK inhibitors

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p53, the cellular gatekeeper for growth and division

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A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

21 January 2018

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

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Twenty years of p53 research: structural and functional aspects of the p53 protein

21 January 2018

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Mechanisms of switching on p53: a role for covalent modification?

21 January 2018

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Chemical inhibitors of cyclin-dependent kinases

21 January 2018

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Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

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Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

21 January 2018

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Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation

21 January 2018

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Cyclin-dependent regulation of G1 in mammalian fibroblasts.

21 January 2018

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Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

21 January 2018

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The nucleolus: an old factory with unexpected capabilities

21 January 2018

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Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts

21 January 2018

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A Restriction Point for Control of Normal Animal Cell Proliferation

21 January 2018

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G1 events and regulation of cell proliferation

21 January 2018

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Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2

21 January 2018

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Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

21 January 2018

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Different roles for cyclins D1 and E in regulation of the G1-to-S transition

21 January 2018

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Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

21 January 2018

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Synthesis of labile, serum-dependent protein in early G 1 controls animal cell growth

21 January 2018

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Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Drug-induced dispersal of transcribed rRNA genes and transcriptional products: immunolocalization and silver staining of different nucleolar components in rat cells treated with 5,6-dichloro-beta-D-ribofuranosylbenzimidazole

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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In vivo release of mitotic silencing of ribosomal gene transcription does not give rise to precursor ribosomal RNA processing

21 January 2018

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A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Inhibition of cyclin-dependent kinases by purine analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Cell-cycle inhibitors: three families united by a common cause

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Cyclin A is required in S phase in normal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

Association of human cyclin E with a periodic G1-S phase protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

7 January 2021

A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

7 January 2021

Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

7 January 2021

Alternative pre-rRNA processing pathways in human cells and their alteration by cycloheximide inhibition of protein synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

7 January 2021

A family of human cdc2-related protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

7 January 2021

Cyclin A is required at two points in the human cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

7 January 2021

The labelling index of human and mouse tumours assessed by bromodeoxyuridine staining in vitro and in vivo and flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204741

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204741

1 reference

Dimensions Publication ID

23 September 2017

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1 reference