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p53: puzzle and paradigm (Q29618407)

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scientific article (publication date: May 1996)

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English	p53: puzzle and paradigm	scientific article (publication date: May 1996)

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scholarly article

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p53: puzzle and paradigm (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=8654922

30 April 2017

author name string

Ko LJ

1

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30 April 2017

Prives C

2

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30 April 2017

publication date

1 May 1996

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30 April 2017

language of work or name

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=8654922

30 April 2017

Genes & Development

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30 April 2017

10

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30 April 2017

9

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30 April 2017

1054-72

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30 April 2017

publication type of scholarly work

1 reference

Europe PubMed Central

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.7973727

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

2 references

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1073/PNAS.92.18.8493

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Wild-type p53 binds to the TATA-binding protein and represses transcription

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Microinjection of monoclonal antibody to protein p53 inhibits serum-induced DNA synthesis in 3T3 cells

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Wild-type human p53 transactivates the human proliferating cell nuclear antigen promoter

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

PAK1, a gene that can regulate p53 activity in yeast

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Small peptides activate the latent sequence-specific DNA binding function of p53.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Augmented DNA-binding activity of p53 protein encoded by a carboxyl-terminal alternatively spliced mRNA is blocked by p53 protein encoded by the regularly spliced form

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Inhibition of cyclin-dependent kinases by p21

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Induction of apoptosis in HeLa cells by trans-activation-deficient p53

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53 modulation of TFIIH–associated nucleotide excision repair activity

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Essential role for p53-mediated transcription in E1A-induced apoptosis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53 deficiency does not affect the accumulation of point mutations in a transgene target

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Growth factor modulation of p53-mediated growth arrest versus apoptosis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Solution structure of the tetrameric minimum transforming domain of p53

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Cyclin E restores p53 activity in contact-inhibited cells

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Role of cysteine residues in regulation of p53 function

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Refined solution structure of the oligomerization domain of the tumour suppressor p53

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Structure of the NF-kappa B p50 homodimer bound to DNA

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Two cellular proteins that bind to wild-type but not mutant p53

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Mutational spectrum of the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Mediation of c-Myc-induced apoptosis by p53.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Sequence-specific transcriptional activation is essential for growth suppression by p53.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p21 is a universal inhibitor of cyclin kinases

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Activation of the cryptic DNA binding function of mutant forms of p53.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

p53-mediated cell death: relationship to cell cycle control

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

The p53 protein is an unusually shaped tetramer that binds directly to DNA.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Thymocyte apoptosis induced by p53-dependent and independent pathways

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Life, death, and the pursuit of apoptosis.

1 reference

https://www.researchgate.net/publication/14545487_p53_Puzzle_and_paradigm#references

p53: Puzzle and paradigm (English)

Identifiers

10.1101/GAD.10.9.1054

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=8654922

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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