Regulation of p53 in embryonic stem cells (Q42825893)

8 November 2017

Regulation of p53 in embryonic stem cells (English)

1 reference

8 November 2017

Valeriya Solozobova

1

1 reference

PubMed ID

20542030

8 November 2017

Christine Blattner

series ordinal

2

1 reference

PubMed ID

20542030

8 November 2017

language of work or name

English

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publication date

11 June 2010

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Experimental Cell Research

8 November 2017

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8 November 2017

316

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8 November 2017

2434-2446

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8 November 2017

15

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8 November 2017

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Live or let die: the cell's response to p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

The mitochondrial p53 pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulation of p53 function and stability by phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

The ubiquitin ligase COP1 is a critical negative regulator of p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Life, death, and ubiquitin: taming the mule.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

The p53-Mdm2 module and the ubiquitin system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Mdm2 promotes the rapid degradation of p53

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulation of p53 stability by Mdm2

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulation of p53--insights into a complex process

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulation of p53 localization and activity by Ubc13.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

MicroRNA-125b is a novel negative regulator of p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

MicroRNA 125a and its regulation of the p53 tumor suppressor gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

p53: a new player in reproduction

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

The p53 family in differentiation and tumorigenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Temporal dissection of p53 function in vitro and in vivo

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

p53 suppresses the self-renewal of adult neural stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulation of ES cell differentiation by functional and conformational modulation of p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Nuclear accumulation and activation of p53 in embryonic stem cells after DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Hypophosphorylation of Mdm2 augments p53 stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Protocol: a highly sensitive RT-PCR method for detection and quantification of microRNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Embryonic stem cell differentiation: emergence of a new era in biology and medicine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

MicroRNAs: genomics, biogenesis, mechanism, and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-alpha3 binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

MDM2-dependent ubiquitination of nuclear and cytoplasmic P53

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Mapping of the p53 and mdm-2 interaction domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Binding of p53 to the central domain of Mdm2 is regulated by phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

The central region of HDM2 provides a second binding site for p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Regulation of mouse embryonic stem cell neural differentiation by retinoic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Differentiation of mouse embryonic stem cells into a defined neuronal lineage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Proteomic characterization of early-stage differentiation of mouse embryonic stem cells into neural cells induced by all-trans retinoic acid in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Nuclear exclusion of wild-type p53 in immortalized human retinoblastoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Novel patterns of p53 abnormality in breast cancer from Taiwan: experience from a low-incidence area

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Functional inactivation but not structural mutation of p53 causes liver cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Parc: a cytoplasmic anchor for p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

The multiple levels of regulation by p53 ubiquitination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

C-terminal ubiquitination of p53 contributes to nuclear export

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Stress-induced p53 runs a transcription-independent death program

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

p53 has a direct apoptogenic role at the mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Transcription-independent pro-apoptotic functions of p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

UBC13, a DNA-damage-inducible gene, is a member of the error-free postreplication repair pathway in Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.06.006

10.1016/J.YEXCR.2010.06.006

7 January 2021

Identifiers

DOI

1 reference

8 November 2017

1 reference

PubMed ID

20542030