High affinity insertion/deletion lesion binding by p53. Evidence for a role of the p53 central domain (Q40977497)

25 September 2017

title

High affinity insertion/deletion lesion binding by p53. Evidence for a role of the p53 central domain (English)

1 reference

25 September 2017

Szak ST

1

1 reference

25 September 2017

Pietenpol JA

series ordinal

2

1 reference

25 September 2017

language of work or name

English

0 references

publication date

1 February 1999

1 reference

Journal of Biological Chemistry

25 September 2017

published in

1 reference

25 September 2017

volume

274

1 reference

25 September 2017

issue

6

1 reference

25 September 2017

page(s)

3904-3909

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

25 September 2017

1 reference

Mutations in the p53 gene occur in diverse human tumour types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Sequence-specific transcriptional activation is essential for growth suppression by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Mediation of c-Myc-induced apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

The tumor suppressor p53 is bound to RNA by a stable covalent linkage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Binding of a simian virus 40 T antigen-related protein to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Interaction of p53 with its consensus DNA-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Regulation of the specific DNA binding function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Redox state regulates binding of p53 to sequence-specific DNA, but not to non-specific or mismatched DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Inhibition of DNA replication factor RPA by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

The DNA damage-recognition problem in human and other eukaryotic cells: the XPA damage binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

DNA damage recognition by XPA protein promotes efficient recruitment of transcription factor II H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Reaction mechanism of human DNA repair excision nuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

In vivo evidence for binding of p53 to consensus binding sites in the p21 and GADD45 genes in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Double strand breaks induced by low doses of gamma rays or heavy ions: quantitation in nonradioactive human DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Induction of cell cycle arrest by the endogenous product of lipid peroxidation, malondialdehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

The in vitro phosphorylation of p53 by calcium-dependent protein kinase C--characterization of a protein-kinase-C-binding site on p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

Demonstration of DNA damage/repair in individual cells using in situ end labelling: association of p53 with sites of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.6.3904

21 January 2018

Identifiers

DOI

10.1074/JBC.274.6.3904

1 reference

25 September 2017

1 reference