Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus (Q38294071)

1 September 2017

title

Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus (English)

1 reference

1 September 2017

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus (English)

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(05)80007-8

6 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7600571

6 June 2024

author name string

J. Jayaraman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7600571

6 June 2024

C. Prives

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7600571

6 June 2024

publication date

1 June 1995

1 reference

1 September 2017

30 June 1995

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7600571

https://doi.org/10.1016/s0092-8674(05)80007-8

6 June 2024

language of work or name

English

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work available at URL

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7600571

https://api.elsevier.com/content/article/PII:S0092867405800078?httpAccept=text/xml

6 June 2024

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(05)80007-8

https://api.elsevier.com/content/article/PII:S0092867405800078?httpAccept=text/plain

6 June 2024

1 reference

https://api.crossref.org/works/10.1016/S0092-8674(05)80007-8

6 June 2024

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1 September 2017

volume

81

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1 September 2017

issue

7

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1 September 2017

page(s)

1021-1029

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p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

1 September 2017

cites work

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7 January 2021

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

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A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

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Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation

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High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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Inhibition of DNA replication factor RPA by p53.

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WAF1, a potential mediator of p53 tumor suppression

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Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

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Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.

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The transactivator proteins VP16 and GAL4 bind replication factor A.

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Allosteric activation of latent p53 tetramers

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7 January 2021

Regulation of the specific DNA binding function of p53

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Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

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Identification of transcriptional activation and inhibitory domains in serum response factor (SRF) by using GAL4-SRF constructs

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

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7 January 2021

Solution structure of the tetrameric minimum transforming domain of p53

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The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication

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7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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Casein kinase II enhances the DNA binding activity of serum response factor

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

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p53-catalyzed annealing of complementary single-stranded nucleic acids

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7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

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7 January 2021

Mechanisms of DNA excision repair

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7 January 2021

p53 function and dysfunction

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7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions

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Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids

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7 January 2021

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

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7 January 2021

Human p53 directs DNA strand reassociation and is photolabelled by 8-azido ATP

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Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

6 June 2024

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Database of p53 gene somatic mutations in human tumors and cell lines

6 June 2024

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The mdm-2 gene is induced in response to UV light in a p53-dependent manner

6 June 2024

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DNA-binding Properties of the p53 Tumor Suppressor Protein

6 June 2024

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6 June 2024

Identifiers

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1 September 2017

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