Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus (Q38294071)

1 September 2017

Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus (English)

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1 September 2017

Jayaraman J

1

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PubMed ID

7600571

1 September 2017

Prives C

series ordinal

2

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PubMed ID

7600571

1 September 2017

language of work or name

English

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publication date

1 June 1995

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1 September 2017

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1 September 2017

81

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1 September 2017

1021-1029

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1 September 2017

7

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p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

1 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

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https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation

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https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Inhibition of DNA replication factor RPA by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

The transactivator proteins VP16 and GAL4 bind replication factor A.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Allosteric activation of latent p53 tetramers

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https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Regulation of the specific DNA binding function of p53

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https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Identification of transcriptional activation and inhibitory domains in serum response factor (SRF) by using GAL4-SRF constructs

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Solution structure of the tetrameric minimum transforming domain of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Casein kinase II enhances the DNA binding activity of serum response factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

p53-catalyzed annealing of complementary single-stranded nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Mechanisms of DNA excision repair

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

p53 function and dysfunction

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https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

1 reference

7 January 2021

Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2805%2980007-8

7 January 2021

10.1016/S0092-8674(05)80007-8

Identifiers

DOI

1 reference

1 September 2017

1 reference

PubMed ID

7600571