p53-independent upregulation of p21WAF1 in NIH 3T3 cells malignantly transformed by mot-2. (Q40812450)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11305325%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

p53-independent upregulation of p21WAF1 in NIH 3T3 cells malignantly transformed by mot-2 (English)

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6 November 2019

4

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6 November 2019

author name string

Takano S

series ordinal

1

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6 November 2019

Wadhwa R

series ordinal

2

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6 November 2019

Mitsui Y

series ordinal

3

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6 November 2019

publication date

1 March 2001

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6 November 2019

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6 November 2019

volume

11

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6 November 2019

issue

1

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6 November 2019

page(s)

55-60

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https://scigraph.springernature.com/pub.10.1038/sj.cr.7290066

6 November 2019

exact match

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cites work

p53, the cellular gatekeeper for growth and division

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p53--an acrobat in tumorigenesis

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Redundant down-regulation pathways for p53.

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p21--negative regulator of the cell cycle

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New functional activities for the p21 family of CDK inhibitors

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

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Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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Radiation-induced cell cycle arrest compromised by p21 deficiency

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Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member.

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Malignant transformation of NIH3T3 cells by overexpression of mot-2 protein.

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NIH 3T3 cells malignantly transformed by mot-2 show inactivation and cytoplasmic sequestration of the p53 protein

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Increased activity of p53 in senescing fibroblasts

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Identification of genetic events involved in early steps of immortalization of mouse fibroblasts.

21 January 2018

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Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

21 January 2018

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Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status

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Induction of senescence in human malignant glioma cells by p16INK4A.

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Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation.

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The tumor suppressor protein p16INK4a.

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Enhanced expression of multiple forms of VEGF is associated with spontaneous immortalization of murine fibroblasts.

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Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

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Immunohistochemical expression of mdm2 and p21WAF1 in invasive cervical cancer: correlation with p53 protein and high risk HPV infection

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Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression

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Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F.

21 January 2018

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Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

21 January 2018

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7 January 2021

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53

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7 January 2021

Genes involved in the control of cellular proliferative potential

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7 January 2021

Regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1/Sdi1) gene expression in hepatic regeneration

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

Correlation and prognostic significance of p53, p21WAF1/CIP1 and Ki-67 expression in patients with superficial bladder tumors treated with bacillus Calmette-Guerin intravesical therapy

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7 January 2021

Identifiers

DOI

10.1038/SJ.CR.7290066

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11305325%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 November 2019

0 references

1 reference