p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53 (Q77853882)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

author name string

Fang L

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Igarashi M

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Leung J

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Sugrue MM

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Lee SW

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Aaronson SA

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

language of work or name

English

0 references

publication date

1 May 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

2789-2797

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362249%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202615

8 December 2019

exact match

0 references

cites work

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

1 reference

7 January 2021

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Replicative senescence: an old lives' tale?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Growth factor modulation of p53-mediated growth arrest versus apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

p21WAF1 induces permanent growth arrest and enhances differentiation, but does not alter apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Inhibition of cyclin-dependent kinases by p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Evidence for a p53-independent pathway for upregulation of SDI1/CIP1/WAF1/p21 RNA in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Mutated p21(WAF1/CIP1/SDI1) lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Growth suppression by p16ink4 requires functional retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

The pathway of cell senescence: WI-38 cells arrest in late G1 and are unable to traverse the cell cycle from a true G0 state

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Cyclins and cyclin-dependent kinases: a biochemical view

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Human bladder carcinoma cell lines as indicators of oncogenic change relevant to urothelial neoplastic progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Mechanisms of DNA excision repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Mechanism of activation of a human oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Induction of senescence in human malignant glioma cells by p16INK4A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Increased expression of p21Sdi1 in adrenocortical cells when they are placed in culture.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Proliferative capacity and DNA content of aging human diploid cells in culture: a cytophotometric and autoradiographic analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021

Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202615

7 January 2021